Universiteit Leiden

Academisch Ziekenhuis Leiden (h.o.d.n. Lumc)

Michael Keith Richardson

Jan Wouter Drijfhout

Gilles Philippus Van Wezel

Petrus Hendricus Nibbering

Robert Alexander Cordfunke

Harald Martijn Ijsbrand Kerkkamp

Michella Manon Voet

Marinus Bernardus Olde Riekerink

Johannes Oonk

Elwin Xander Vrouwe

Eric Marijn Wielhouwer

The disclosure concerns snake-derived peptides and the useful application of such peptides to inhibit bacterial, fungal, viral and parasitic infections. The disclosed peptides are also useful for the treatment of an inflammatory condition or cancers.

Bioactive peptides derived from snakes

A biological microfluidics chip comprising a substrate, a microfluidic inlet port defining an opening in a surface of the substrate, and a microfluidic outlet port defining an opening in a surface of the substrate. The biological microfluidics chip also comprises a plurality of wells extending from a top surface of the substrate, wherein each well is bounded by one or more walls, and an inlet opening and an outlet opening are provided in a wall of each of the plurality of wells. An inlet microfluidic channel is provided in the substrate to connect the microfluidic inlet port to each of the inlet openings in the walls of the wells, and an outlet microfluidic channel is provided in the substrate to connect each of the outlet openings in the walls of the wells to the microfluidic outlet port.

Biological microfluidics chip and related methods

Growing community of inventors

Leiderdorp, Netherlands

Michael Keith Richardson