Basf Aktiengesellschaft

Basf Se Corporation

Roche Diabetes Care, Inc.

Roche Diagnostics Operations, Inc.

Technische Universitaet Muenchen

Basf Aktiengesellschaft, Patentabteilung

Roche Diagnostics Gmbh

Merial Limited

F. Hoffmann-la Roche Ag

Basf Agro B.v. Arnhem (nl), Zurich Branch

Reinhard, Robert

Hamprecht, Gerhard

Puhl, Michael

Seitz, Werner

Michael Keil

Michael Rack

Bruno Wuerzer

Bernd Wolf

Joachim Gebhardt

Dieter Jahn

Rainer Becker

Ulrich Schirmer

Norbert Meyer

Volker Maywald

Dieter Kolassa

Wilhelm Rademacher

Rene Lochtman

Wolfgang Von Deyn

Johann Jung

Uwe Josef Vogelbacher

Thomas Weiss

Matthias Witschel

Ernst Baumann

Helmut Hagen

Thomas Zierke

Horst Wingert

Norbert Götz

Christopher Koradin

Maximilian Dochnahl

Frederik Menges

Norbert Goetz

Joachim Rheinheimer

Hans List

Guido Mayer

Frank Deck

Norbert G&ouml;tz

Thomas Schmidt

Gerhard Hamprecht

Ulf Misslitz

Robert Reinhard

Werner Seitz

Wolfgang Spiegler

Heinz Isak

Thomas Grote

Juergen Kast

Ahmet Konya

Michael Puhl

Thomas Wettling

Timo Frassetto

Hubert Sauter

Wassilios Grammenos

Albrecht Harreus

Herbert Bayer

Walter Himmele

Ralf Klintz

Jochen Dietz

Hans Ziegler

Roland G&ouml;tz

Hans-Juergen Kuhr

Eberhard Ammermann

Gisela Lorenz

Jochem Henkelmann

Cyrill Zagar

Hans-Peter Haar

Hans Theobald

Joachim Hoenes

Ernst Buschmann

Andreas Gypser

Jan Klaas Lohmann

Bernd Sievernich

Costin Rentzea

Peter Erk

Norbert Gotz

Armin Stamm

Gerhard Cox

Oliver Kube

Uwe Kraemer

Thomas Z Harkin

Horst Hartmann

Karl Miltner

Heidi Emilia Saxell

Karl-Otto Westphalen

Siegfried Strathmann

Joaquim Henrique Teles

Markus Gewehr

Steven Nelson Roe

Herbert Harttig

Wolfgang Rohr

Hardo Siegel

Volker Harries

Bernd Mueller

Bernd W M&uuml;ller

Bernd Muller

Bernd Zeeh

Stefan Engel

Volker Zimmer

Oliver Wagner

Bernd Müller

Ruth Muller

Roland Goetz

Horst Mayer

Arne Ptock

Hartmann Konig

Charles C Raney

The present application concerns a system for the withdrawal of body fluids comprising a coupled tensioning and triggering mechanism, wherein the triggering mechanism is mechanically coupled to the tensioning mechanism in such a manner that the puncturing process is automatically triggered by successive continuation of the tensioning movement when the tensioning mechanism is actuated and wherein the lancing process triggered in this manner is carried out by a lancet.

Lancing aid having automatic triggering

A lancet magazine for use in a lancing aid is described comprising a plurality of lancets each having a lancet body at the proximal end of the lancet and a lancet tip at the distal end of the lancet, where the proximal end of the lancet points in the direction of the proximal end of the housing of the lancet magazine and the distal end of the lancet is aligned in the direction of the distal end of the housing and the lancets in the unused state are completely surrounded by the housing. Furthermore, an extension unit is movably connected to the housing in such a manner that the housing can be extended by movement of the extension unit in the direction of the distal end of the housing such that the lancet is prevented from emerging from the lancet magazine.

Method of reuse protection for lancet system

An insertion device including an insertion needle holder and a drive mechanism for linearly moving the insertion needle holder in a puncturing direction. The insertion needle holder also includes at least one actuating element for actuating a drive mechanism. The drive mechanism converts a driving motion of the actuating element, which extends transversely or opposite to the puncturing direction, into a puncturing motion of the insertion needle holder.

Insertion device

A puncturing system has a carrier tape carrying multiple lancets, a device housing comprising a conveying facility for moving the lancets into a usage position consecutively by moving the carrier tape in a conveying direction, a puncturing drive for accelerating one of the lancets that is positioned in the usage position in a puncturing motion, an opening in the device housing for touching against a body part in which a puncture is to be made by the puncturing motion of one of the lancets, an actuation facility for driving the conveying facility, and an unlockable interlock comprising a stop that blocks further transport of the carrier tape as soon as one of the lancets has reached the usage position.

Puncturing system and lancet carrier tape

Disclosed is a puncturing system for generating a puncture wound for obtaining a sample of a body fluid, comprising a press-on part to be pressed onto a body part in which a puncture wound is to be generated, a trigger, by the actuation of which a user can trigger a puncturing motion of a puncturing element after the press-on part is pressed on, and a testing facility for determining at least one test parameter on which a sample-obtaining probability depends. A securing facility is also provided that, in a locked state, locks the trigger such that no puncturing motion can be triggered, and, in a triggering state, releases the trigger such that a puncturing motion can be triggered by actuation thereof, whereby the securing facility is transitioned from the locked state to the triggering state by the testing facility when the test parameter determined by the testing facility meets defined minimum requirements. A signaling facility is also provided for signaling a transition of the securing facility to the triggering state and/or for signaling that the securing facility is in the triggering state. Also disclosed is a method for preparing a puncturing system for generating a puncture wound.

Puncturing system

The present invention relates to a process for preparing sulfuric diamides of the general formula IRRN&#x2014;S(O)&#x2014;NH&#x2003;&#x2003;(I)in which Rand Rare each independently a primary alkyl radical having from 1 to 8 carbon atoms, a secondary alkyl radical having from 3 to 8 carbon atoms or a cycloalkyl radical having from 5 to 8 carbon atoms, or, together with the nitrogen atom, form a 5- to 8-membered, saturated nitrogen heterocycle which, as well as the nitrogen atom, may have a further heteroatom selected from O and S as a ring member, where the nitrogen heterocycle is unsubstituted or may have 1, 2, 3 or 4 alkyl groups having in each case from 1 to 4 carbon atoms as substituents. The process comprises the following steps:

Methods for producing sulfonic acid diamides

Reuse protection for lancet system

An insertion device includes an insertion needle holder and a drive mechanism for linearly moving the insertion needle holder in a puncturing direction. The insertion needle holder also includes at least one actuating element for actuating a drive mechanism. The drive mechanism converts a driving motion of the actuating element, which extends transversely or opposite to the puncturing direction, into a puncturing motion of the insertion needle holder.

The test strip stabilizes skin prior to incision by a lancet tip. The innovative test strip includes a pair of skin contacting tabs that apply pressure linearly to the skin to stretch the skin taut. Beneficially an incision by a lancet tip to an accurate depth can be formed on the taut skin. Moreover, pressure from the tabs is applied linearly to the skin which results in a higher ratio of pressure to surface that can be reached as compared to applying pressure laminarily to skin. Some manufacturing techniques of the skin contacting tabs include cutting or stamping through all of the layers and test area of the test strip to form these tabs. These techniques increase the manufacturing efficiency and cost savings associated with test strips and integrated lancet testing devices. Contamination from other sampling events is eliminated since the test strips are disposed of after each use.

Test strip with a shaped tip for skin straightening

Lancing device

The present invention relates to a process for manufacturing aryloxyacetamides of formula (I), by reacting haloacetamides of formula (II) with a phenol of formula (III); wherein the variables are defined according to the description, and aryloxyacetamides of formula (I).

Process for manufacturing aryloxyacetamides

The present invention relates to a process for manufacturing a benzoxazinone of formula (I), by reacting a nitro compound of formula (II) with a reducing agent to obtain an amino compound of formula (III), and then reacting the amino compound of formula (III) with an acid; wherein the variables are defined according to the description, and benzoxazinone of formula (I).

Process for manufacturing benzoxazinones

A process for manufacturing 5-chloromethyl-2,3-pyridine dicarboxylic acid anhydrides (I)   Compounds (I) are useful intermediates in the synthesis of herbicidal imidazolinones.

Process for manufacturing 5-chloromethyl-2,3-pyridine dicarboxylic acid anhydrides

Adjustment mechanisms are used in conjunction with integrated lancet test strips to adjust the position of the drive system, engagement system, or the drive coupling in a fixed stroke lancing system to thereby adjust the penetration depth of the lancet. In a variable drive stroke lancing system, the lancet penetration depth is adjusted by changing the stroke length of a drive system. The stroke length of a drive system is adjusted by rotating a cam or sliding a cam in a cam type drive system. In either the fixed or the variable drive stroke lancing system, the test strip and/or guidance foil of the integrated lancet test strip is immobilized while the lancet is actuated.

Lancet drive system depth control method and test strip location methods

Growing community of inventors

Freinsheim, Germany

Michael Keil