Novartis Ag

Alcon, Inc.

Alcon Laboratories, Inc.

Alcon Research, Ltd.

Alcon Manufacturing, Ltd.

Specialeyes, LLC

Michael John Simpson

Mutlu Karakelle

Xin Hong

Xiaoxiao Zhang

Yan Zhang

Jihong Xie

Myoung Choi

Stephen J Van Noy

Myoung-Taek Choi

Charles Freeman

Stephen Edward Brauner

Daniel Robert Carson

Chun-Shen Lee

Dan Stanley

An apparatus for generating simulated images includes an input device, a processor and a display device. The input device is configured to input information on a pupil of an eye and design information for a multifocal lens. The processor is configured to generate, based on the inputted pupil information and design information, a simulated image that is visible to the eye when the multifocal lens is disposed in the eye. The display device is configured to display the simulated image generated by the processor.

Multifocal lens and system and method for simulating the same

In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., &#xbd;) of a design wavelength (e.g., a wavelength or about 550 nm).

Extended depth of focus (EDOF) lens to increase pseudo-accommodation by utilizing pupil dynamics

In certain embodiments, determining physical lengths of an eye includes determining an optical length of each segment of a plurality of segments of an axis of the eye, where each segment corresponds to a portion of the eye. A refractive index is determined for each segment. A physical length of each segment is determined according to the optical length and the refractive index of the segment.

Determining physical lengths in an eye using multiple refractive indices

In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., &#xbd;) of a design wavelength (e.g., a wavelength of about 550 nm).

In certain embodiments, calculating intraocular lens (IOL) power includes determining locations of parts of an eye along an axis of the eye. The locations include the location of a cornea, the anterior and posterior locations of a crystalline lens, and the location of a retina. An IOL location of an IOL is calculated according to the anterior and posterior locations of the crystalline lens. Corneal data is also determined. The IOL power is calculated using the corneal data, the IOL location, and the retinal location. In certain embodiments, refractive indices are determined for segments of the axis, and at least one location is adjusted according to the refractive indices.

Calculating an intraocular lens (IOL) power according to a directly determined IOL location

A method and system for measuring an optical property of a multi-focal lens are disclosed. One embodiment of the method comprises: filtering out light transmitted by all but one of a plurality of diffraction orders of the lens to provide an unfiltered light from a single diffraction order; receiving the unfiltered light at a wavefront detector; and analyzing the unfiltered light at the wavefront detector to measure the optical property. The multi-focal lens can be a multi-focal diffractive intra-ocular lens. The measured optical property can be a discontinuity in the lens surface. Filtering can comprise blocking all but the unfiltered light using an aperture operable to let through the unfiltered light from the single diffraction order, and/or blocking all but the unfiltered light using an opaque obstruction operable to let through only a selected amount of light corresponding to the light transmitted by the single diffraction order. The method can further comprise generating an image quality parameter, such as a modulation transfer function, based on the measured optical property.

Method of measuring diffractive lenses

A method for measuring the optical properties of multifocal ophthalmic lenses. Collimated light is passed through an ophthalmic lens and onto an array of lenslets. Light exiting the array of lenslets is detected by a sensor. Blurred spots and/or double spots may represent diffractive zones of the wavefront. A centroid of the spot or a brighter of two spots may be used to determine the lateral position of the spot. Theoretical calculations, laboratory measurements, clinical measurements and experimental image spots may be generated, compared and cross-checked to determine a monofocal equivalent lens. A Modulation Transfer Function (MTF) may be used to evaluate and compare a diffractive lens and a monofocal equivalent lens.

In one aspect, the present invention provides a diffractive ophthalmic lens (e.g., a diffractive IOL) that includes an optic having an anterior surface and a posterior surface, where the optic provides a far focus. A frustrated diffractive structure comprising a plurality of diffractive zones is disposed on at least one of those surfaces so as to provide a near focus. Each zone is separated from an adjacent zone by a zone boundary that imparts an optical delay to the incident light. Further, at least two consecutive zone boundaries are configured such that a difference between their associated phase delays for at least one wavelength of the incident light is greater than about &#xbc; wavelength so as to direct a portion of the incident light to a location between the near and far foci.

Apodized diffractive IOL with frustrated diffractive region

In one aspect, the present invention provide an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior optical surface and a posterior optical surface, where the optic provides an optical power in a range of about 16 D to about 25 D as measured in a medium having an index of refraction substantially similar to that of the eye's aqueous humor (e.g., about 1.336). At least one of the optical surfaces is characterized by an aspherical base profile such that the optic exhibits a negative spherical aberration in a range of about &#x2212;0.202 microns to about &#x2212;0.190 microns across the power range.

Intraocular lens

The present invention provides monofocal ophthalmic lenses that exhibit extended depth of field while providing sufficient contrast for resolution of an image over a selected range of defocus distances. In some embodiments, a lens of the invention can include a refractive surface having controlled surface modulations relative to a base profile. The surface modulations are designed to extend a depth of field of the lens such that a single image can be resolved, albeit with somewhat less contrast, over a range of distances greater than the focal region of a conventional lens. The ophthalmic lenses of the invention can be employed in various vision correction applications, including, but not limited to, intraocular lenses, contact lenses, instrastromal implants and other refractive devices.

Aspheric lenses

A method of selecting an intraocular lens material for toric lenses is disclosed. The method comprises determining the tack of the material.

Toric intraocular lens material

A diffractive, multifocal ophthalmic lens including an apodization zone with echelettes having a smoothly reduced step height to shift the energy balance from the near image to the distant image and thus reduce the glare perceived when viewing a discrete, distant light source.

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Arlington, TX, United States of America

Michael John Simpson