W. L. Gore & Associates, Inc.

Gore Enterprise Holdings, Inc.

Northwestern University

Wayne D. House

Edward H. Cully

Michael J. Vonesh

Jeffrey B. Duncan

Keith M. Flury

Vrad W. Levering

Paul D. Goodman

Jason M. Wiersdorf

Philip P. Off

Daniel M. O'shea

Michael J Vonesh

Edward H Cully

Jeffrey B Duncan

Benjamin M Trapp

Joseph R Armstrong

Mark Joseph Ulm

Carey V Campbell

Edward Emil Shaw

Rachel Radspinner

Keith M Flury

Douglas S Paget

Jason M Wiersdorf

John E Bacino

Aaron J Hopkinson

James William Mann

Craig T Nordhausen

Sherif A Eskaros

Wayne D House

Thomas R McDaniel

Paul D Goodman

Peter J Roeber

Juan C Parodi

John M Squeri

Joseph A Huppenthal

Keith Knisley

Cody L Hartman

Charles J Flynn

Robert L Cleek

George N Foutrakis

John Cheer

Larry J Kovach

Woodrow W Watson

Brandon C Short

Gregory M Lanza

Mei Li

Charles F White

Bruce M Steinhaus

Nathan L Friedman

Thomas G Triebes

Eric M Tittelbaugh

Paul Christopher Begovac

Theresa A Holland

Daniel F Davidson

James Todd Walter

Thane L Kranzler

Peter Heicksen

Eric H Zacharias

Byron K Hayes

John M Brinkmann

Philip P Off

Vrad W Levering

Jeremy P Young

Daniel M O'Shea

Thomas R Mcdaniel

Daniel M O'shea

Jason J Strid

James W Chang

Erin B Hutchinson

Marisa L Sylvester

Daniel W Yates

Douglas F Pajot

Vishnu T Marla

Paul A Silvagni

Steven R Bruun

Margaret L Gallegos

Warren Cutright

Gerald Ray Martin

Melvin E Klegerman

Lyle F Mockros

David D McPherson

Joseph P Armstrong

Fouad H Khasho

M Hayat Onyuksel

David L McPherson

Charles Davidson

Ashwin Nagaraj

Krishnan B Chandran

John M Fildes

Ryan V Peterson

K Jason Nackard

Chaokang Chu

Dennis L Salzmann

Krzysztof R Pietrzak

Warren J Cutright

Ace M Baty

Joshua D Williams

Melissa J Matzen

Keith A Knisley

James W Mann

Mark E Trokanski

A diametrically adjustable endoprosthesis includes a controlled expansion element extending along at least a portion of a graft and is supported by a stent. The controlled expansion element diametrically constrains and limits expansion of the endoprosthesis. Upon deployment from a smaller, delivery configuration, the endoprosthesis can expand to the initial diameter set by the controlled expansion element. Thereafter, the endoprosthesis can be further diametrically expanded (e.g., using balloon dilation) by mechanically altering the controlled expansion element.

Diametrically adjustable endoprostheses and associated systems and methods

Embodiments of the present disclosure comprise occlusion and drug delivery devices and methods. One aspect of the disclosure comprises a drug delivery device comprising an inner expansion member and an outer drug delivery component. Another aspect of the disclosure comprises bioabsorbable, lumen-occluding implants.

Vascular occlusion and drug delivery devices, systems, and methods

A retrieval catheter operable by a single clinician that will neither displace a deployed stent nor cause undue trauma to the vascular lumen or lesion. The retrieval catheter may be sized to accommodate both a guidewire and a balloon wire. The retrieval catheter is easy to navigate through tortuous passageways and will cross a previously deployed stent or stent-graft easily with minimal risk of snagging on the deployed stent or stent graft. The sheath and dilator are adapted to allow a guidewire or balloon wire to pass through the walls of both and to allow the sheath and dilator to move axially with respect to each other.

Retrieval catheter

In various embodiments, a device is provided comprising a balloon configured to expand to an expanded state in response to introduction of a fluid at a first pressure, wherein the fluid perfuses through the balloon above a second pressure, the second pressure being the same or greater than the first pressure. In various embodiments, a method comprising fabricating a balloon configured to expand to an expanded state in response to introduction of a fluid at a first pressure, wherein the fluid perfuses through the balloon above a second pressure, the second pressure being at or greater than the first pressure, disposing the balloon on an elongate member having a lumen, placing the lumen in fluid communication with an interior volume of the balloon.

Controlled porosity devices for tissue treatments, methods of use, and methods of manufacture

The invention is an improved biocompatible surface for a variety of medical purposes. The biocompatible surface employs a unique tight microstructure that demonstrates enhanced cellular response in the body, particularly when placed in contact with blood. As a blood contact surface, the present invention can be beneficially employed in a wide variety of implantable devices and in many other devices and equipment that come in contact with blood.

Biocompatible surfaces and devices incorporating such surfaces

The present disclosure includes an endoprosthesis delivery system comprising an elongate member, such as a catheter, an endoprosthesis, a covering member disposed about the endoprosthesis, and at least one flexible element situated between the endoprosthesis and the covering member. The covering member can extend beyond an end of the endoprosthesis. In operation, as the covering member is removed, the flexible element can guide the covering member over the end of the endoprosthesis to prevent entanglement between the end of the endoprosthesis and the covering member.

Endoprosthesis delivery systems with deployment aids

The present invention is directed to a deployment system for an endoluminal device. The deployment system includes a confining sheath placed around a compacted endoluminal device. A deployment line is provided in the system. As the deployment line is actuated, the sheath retracts from around the compacted endoluminal device. Once the sheath is retracted from around the compacted endoluminal device, the endoluminal device is operable to expand. Any remaining sheath material is removed from the implantation site along with the deployment line.

Deployment system for an endoluminal device

Novel catheter constructions comprising thin covering or wrapping materials such as polymer films. A catheter provided with a guidewire catheter lumen having a thin covering that is easily punctured by a guidewire at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. Moreover, polymer film can be used in combination with one or more elements to produce novel catheter constructions.

Catheter assembly

A medical device includes a vessel member, a port that couples a compartment interior of the vessel member to a region exterior of the vessel member, and a tubular member that defines a lumen. A distal end of the tubular member is attached to an internal surface of the vessel member within the compartment so that a portion of the internal surface of the vessel member provides a seal at a distal end of the lumen. The tubular member passes through the port, and the proximal end of the tubular member is configured to remain exterior of the compartment. A delivery of a sufficient amount of a filling material into the lumen of the tubular member causes a length of the tubular member to pass through the port and into the vessel compartment.

Space-filling device

Various embodiments provide a device comprising a balloon assembly including a balloon, a film template, and a rigid element. The film template may have a fixed upper distension limit and may include at least one aperture. The rigid element may lay substantially flush with an outer surface of the balloon at a first inflated state of the balloon. The first upper distension limit of the balloon may be greater than the fixed upper distension limit of the film template and the balloon may outwardly protrude through the at least one aperture at a second inflated state. The rigid element may be extended in a radial direction away from the outer surface of the balloon as the balloon outwardly protrudes through the at least one aperture relative to the outer surface of the film template.

Balloon assemblies having controllably variable topographies

Embodiments herein include devices and methods directed toward creating reverse flow within a vessel and thereby providing protection against embolic debris. Embodiments comprise a catheter and a plurality of occluders that are expandable and adjustable within a lumen to create low-pressure areas that reroute blood flow and embolic debris therein.

Single access flow-reversal catheter devices and methods

Growing community of inventors

Flagstaff, AZ, United States of America

Michael J Vonesh