University of Minnesota

Other

National Institutes of Health, a Component of the US Dept. of Health & Human Services

Arizona State University

Finch Therapeutics Holdings LLC

Hydochar LLC

Michael J Sadowsky

Alexander Khoruts

Matthew J Hamilton

Alexa R Weingarden

Lawrence Philip Wackett

Christopher M Staley

Mervyn L De Souza

Jeremy S Minshull

Thomas Julius Borody

Steven M Heilmann

James Adams

Rosa Krajmalnik-Brown

Frederick J Schendel

Kenneth J Valentas

Alptekin Aksan

Dae-Wook Kang

Eduardo Reategui

Marc Von Keitz

Lisa Kasinkas

Jennifer L Seffernick

Paul A Lefebvre

Carroll P Vance

Deborah A Samac

The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.

Compositions and methods for transplantation of colon microbiota

The present disclosure provides compositions and methods for treatinginfection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of a pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.

Compositions and methods fortreatment

The present disclosure provides compositions and methods for treatinginfection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.

The present disclosure relates to compositions and methods for treating autism spectrum disorder (ASD) by restoring an ASD patient's gut microbiota. These methods can be used with ASD patient with or without ongoing gastrointestinal symptoms. Provided here is a method for ASD treatment in a subject in need thereof comprising or consisting essentially of administering a therapeutic composition comprising a fecal microbe or a fecal microbiota preparation to the subject. Also provided here is a method comprises administering an antibiotic to a human subject; subjecting the human subject to a bowel cleanse; and administering purified fecal microbiota to the human subject. Further provided are evaluation and quantitative characterization of patient symptom improvements upon treatment described here.

Methods for treating autism spectrum disorder and associated symptoms

The present invention relates to compositions for encapsulation of biomaterials in a silica-matrix. The present invention includes a composition for formation of a silica-matrix encapsulated biomaterial. The composition includes a reactive silicon compound and a biomaterial with a catalytic activity. When encapsulated in the silica-matrix, the biomaterial at least partially retains its catalytic activity. The present invention also relates to methods of making silica-matrix encapsulated biomaterials, and to methods of using silica-matrix encapsulated biomaterials, including methods of treating water or gas using the silica-matrix encapsulated biomaterials.

Silica encapsulated biomaterials

Algae-derived synthetic coal and filtrates. The invention described herein provides an algae-derived synthetic coal product and filtrates and process for preparing the same using an improved hydrothermal carbonization process. The synthetic coal product is similar to natural bituminous coal in terms of percent carbon content and energy equivalency while at the same time containing relatively low levels of sulfur and contaminant heavy metals. Unlike natural coal and other fossil fuels, because the carbon of the biomass is formed through photosynthesis, carbon dioxide formed during combustion is a 'carbon neutral' event with little or no 'new' carbon dioxide being added to the earth's atmosphere. The algae-derived filtrates contain useful constituents.

Algal coal and process for preparing same

The present invention relates to stable cyanuric acid hydrolase enzymes, compositions, and devices for use in the treatment of a liquid, such as water. The present invention also relates to methods of using these enzymes, compositions and devices for the treatment of a liquid, such as water.

Methods, compositions and devices utilizing structurally stable cyanuric acid hydrolase

Growing community of inventors

Roseville, MN, United States of America

Michael J Sadowsky