Cardiac Pacemakers, Inc.

University of Minnesota

Michael J Lyden

Qingsheng Zhu

William J Linder

Nicholas J Stessman

Scott M Freeberg

Joseph M Bocek

Michael J Root

Masoud Ameri

Yingbo Li

Mark Gryzwa

Scot C Boon

Lisa B Schmalhurst

Kurt E Koshiol

James Kalgren

Troy A Giese

James E Blood

Jonathan H Kelly

Rajesh Krishan Gandhi

Patrick J Barry

Thomas M Bocek

Randy White

Robert M Mohn

Jeffrey E Stahmann

Scott Thomas Mazar

Gregory J Sherwood

Jeffrey Allen Von Arx

Paul Allan Haefner

Allan Thomas Koshiol

Justin Theodore Nelson

John M Darst

Laura Mepham

Angela M Muttonen

Michael Mathias Freking

Dorothy Marie Nauman

Raia Colette Finc

George D Ritzinger

Scott Hostine

Embodiments herein relate to breath analysis system. In an embodiment, a gas measurement device is included having a housing defining an interior volume. The housing can include a fluid ingress port, a fluid egress port, a bottom wall, and a circuit board disposed within the interior volume. The circuit board can include a first side and a second side, where the first side of the circuit board faces inward toward the interior volume. The circuit board can include a plurality of gas sensors disposed on the first side of the circuit board and a plurality of conductive pads disposed on the second side of the circuit board, wherein a plurality of electrical contacts contact the conductive pads when the circuit board is seated within the housing. Other embodiments are also included herein.

Fluid analysis system

An implantable device, such as a pacer, defibrillator, or other cardiac rhythm management device, can include one or more MRI Safe components. In an example, the implantable device includes a battery including a first electrode and a second electrode separate from the first electrode. The second electrode includes a first surface and a second surface. The second electrode includes a slot through the second electrode from the first surface toward the second surface. The slot extends from a perimeter of the second electrode to an interior of the second electrode. The slot is configured to at least partially segment a surface area of the second electrode to reduce a radial current loop size in the second electrode.

Implantable medical device including eddy current reducing battery

A filtered feedthrough assembly for an implantable medical device comprises a ferrule, an electrical insulator coupled to the ferrule by a connection element, a plurality of feedthrough conductors extending through the electrical insulator, a printed circuit board (PCB), and plurality of capacitors. The PCB is coupled to the ferrule or the electrical insulator, and includes one or more ground layers and a plurality of vias. The connection element is electrically coupled to the ground layer through the vias. The capacitor has a ground terminal electrically coupled to the ground layer through at least one of the vias, and a conductor terminal electrically coupled to the feedthrough conductor.

Filtered feedthrough assembly for implantable medical electronic devices

A filtered feedthrough assembly for an implantable medical device includes a ferrule, an electrical insulator coupled to the ferrule by a connection element, a plurality of feedthrough conductors extending through the electrical insulator, a printed circuit board (PCB), and a plurality of capacitors. The PCB is coupled to the ferrule or the electrical insulator, and includes one or more ground layers and a plurality of vias. The connection element is electrically coupled to the ground layer through the vias. The capacitor has a ground terminal electrically coupled to the ground layer through at least one of the vias, and a conductor terminal electrically coupled to the feedthrough conductor.

An implantable medical device performs impedance measurement and demodulation, such as for obtaining lead impedance measurements, or thoracic impedance measurements, such as for extracting respiration, cardiac stroke, or fluid status information. A 4-point FIR filter demodulator can be used to demodulate a two-phase current excitation waveform. The demodulator can also be used to measure noise for triggering a noise response. Among other things, an increased excitation current level can be used when noise is deemed to be present.

Impedance measurement and demodulation using implantable device

An ambulatory or implantable device, such as a pacer, defibrillator, or other cardiac rhythm management device, can tolerate magnetic resonance imaging (MRI) or other noise without turning on an integrated circuit diode by selectively providing a bias voltage that can overcome an expected induced voltage resulting from the MRI or other noise.

Implantable device with bias for MRI

During auto-threshold, autocapture, or other evoked response sensing, post-pace artifact is reduced by using a smaller coupling capacitor value than what is used when not in such an evoked response sensing configuration. This can be accomplished by borrowing another capacitor for use as the coupling capacitor. The borrowed capacitor can be a backup pacing capacitor from the same or a different pacing channel. The borrowed capacitor can also be a coupling capacitor from a different pacing channel.

Configuration of pacing output channels

An implantable medical device or some other ambulatory medical device, such as a pacer, defibrillator, or other cardiac rhythm management device can include an electrical energy delivery circuit, such as including an integrated circuit comprising a first electrostimulation output terminal, a can terminal, and a switch control output. The ambulatory or implantable device can include at least two switches in series, each including a respective substrate electrically separate from the integrated circuit, and from each other, the switches configured to controllably isolate a conductive housing of the implantable medical device from the can terminal of the integrated circuit, such as in response to the switch control output.

Implantable medical device including controllably isolated housing

An implantable medical device can include a hermetically-sealed implantable housing, an exposed first conductor located on or near the housing, and at least one insulated second conductor located near the exposed first conductor. In an example, the implantable medical device can include an isolation test circuit to provide a test stimulus to the exposed first conductor and configured to measure a portion of the test stimulus coupled to the second conductor.

Implantable medical device including isolation test circuit

One aspect of this disclosure relates to a system for dynamic battery management in implantable medical devices. An embodiment of the system includes two or more devices for measuring battery capacity for an implantable medical device battery. The embodiment also includes a controller connected to the measuring devices. The controller is adapted to combine the measurements from the measuring devices using a weighted average to determine battery capacity consumed. According to various embodiments, at least one of the measuring devices includes a coulometer. At least one of the measuring devices includes a capacity-by-voltage device, according to an embodiment. The system further includes a display in communication with the controller in various embodiments. The display is adapted to provide a depiction of battery longevity in units of time remaining in the life of the implantable medical device battery, according to various embodiments. Other aspects and embodiments are provided herein.

Dynamic battery management in an implantable device

Methods and systems involve adjusting an energy used for safety pacing based on the capture threshold. The safety pacing energy may be adjusted prior to a capture threshold test. During the capture threshold test, backup safety paces are delivered using the adjusted pacing energy. Following suspension of automatic capture verification, the device may enter a suspension mode. During the suspension mode, safety pacing pulses are delivered using a pacing energy adjusted based on capture threshold.

Adaptive safety pacing

Growing community of inventors

Shoreview, MN, United States of America

Michael J Lyden