Other

Revagenix, Inc.

Michael J Lopez

Nikolai Evdokimov

Andrew Calabrese

Frederick Cohen

Timothy Robert Kane

Malken Bayrakdarian

Samuel Desjardins

Darin Hildebrandt

Olivier Soueidan

Ryan Cirz

Logan Andrews

Sanijia Xu

Dale Shanks

Sanjia Xu

John Knox

Henry J Salvatori

Howard A Williams, Jr

The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds and the compounds used in such preparations.

Modular synthesis of aminoglycosides

Provided herein are aminoglycoside compounds, such as compounds of formula (I), (II), (III), (IV), (IVa), (V), (VI), (VIIa), or (VIIb) or pharmaceutically acceptable salts, solvates, stereoisomers, or tautomers of any of the foregoing, useful as therapeutic or prophylactic agents. Also provided herein are methods for their preparation. The compounds may be useful in treating a bacterial infection in a subject, for example a Gram-negative bacterial infection.

Aminoglycosides and uses thereof

A truck ramp including a first ramp element second ramp element and pivoting structure located between the first and second ramp elements. The first ramp element is coupled to the truck at one end and at the other end, a hinge. The second ramp element is hinged at one end and at the other end interlaces with the ground or other surface. Between the first and second ramp elements is a pivoting structure comprised of a first component that is mechanically coupled to the first ramp element at the first hinged end and a second component that is mechanically coupled to the second ramp element at the hinged end. The first component and the second component are rotatable about an axis, orthogonal to the first and second ramp element hinges.

Delivery ramp with an adjustable, rotatable pivot

A truck ramp including a first ramp element, second ramp element and pivoting structure located between the first and second ramp elements. The first ramp element is coupled to the truck at one end and at the other end, a hinge. The second ramp element is hinged at one end and at the other end interfaces with the ground or other surface. Between the first and second ramp elements is a pivoting structure comprised of a first component that is mechanically coupled to the first ramp element at the first hinged end and a second component that is mechanically coupled to the second ramp element at the hinged end. The first component and the second component are rotatable about an axis orthogonal to the first and second ramp element hinges.

Improvements in a cargo holder are disclosed. The cargo hold is configurable to accommodate a variety of different shapes and sizes to retain cargo or boxes in an essentially fixed secure position. Monkey Grabs cargo hold takes the standard four tied down areas in the bed of a vehicle and convert to 24 optional tied down areas. The cargo hold does not include any metal components. The cargo hold has multiple securing loops along lengths of the straps for a user to connect into the ends and along the length of the strap to create additional securing locations. This makes the cargo hold a far more useful cargo hold. The cargo hold is configured in a rectangular configuration to connect along the sides of the bed of a truck and also placed across the bed for more versatile uses of the monkey grip cargo hold.

Monkey grabs cargo hold

The pi&#xf1;ata hanging and swinging apparatus includes a boom pipe that pivots about a vertical support via a pivot point. The boom pipe includes a handle such that the boom pipe can be animated to flail a pi&#xf1;ata up/down/around the vertical support. The boom pipe includes a handle to enable articulation of the boom pipe, and a pulley is located at an end opposite of the handle through which a string extends to hang said pi&#xf1;ata there from. The vertical support is secured to and rotates about a weight block that rests upon the base. An end user stands on the base while articulating the boom pipe in order to animate the pi&#xf1;ata hanging from a string.

Pi&#xf1;ata hanging and swinging apparatus

A system for refacing an existing set of stairs without having to remove the existing set in its entirety or cause destruction to the existing set of stairs and surrounding structure including a stringer refacing component, a stringer cap, a stair tread, a nosing, a cove molding, a riser cap, and a shoe moulding. The stair retread system may be placed over a set of stairs without removing or destroying the staircase as is common with typical staircase refinishing processes.

Step re-tread system and apparatus

The preferred arrangement utilizes a magnet suspended at the center of an elastic cord over a pickup coil. Movement of the magnet is sensed by the coil in that signals are generated by such movement. The signals are processed in the combination of a time delay circuit and a comparator to provide an output which is a measure of acceleration of the element on which the elastic cord is mounted and, in one form, by a measure of jerk in a similar time delay circuit and comparator combination.

Growing community of inventors

Anaheim, CA, United States of America

Michael J Lopez