Hypermed Imaging, Inc.

Hypermed, Inc.

Watervest, LLC

The United States of America, As Represented by the Secretary, Department of Health and Human Services

Masimo Laboratories, Inc.

Argose, Inc.

Hyperspectral Imaging, Inc.

Explotrain, LLC

Michael J Hopmeier

Jenny E Freeman

Derek Brand

Svetlana Panasyuk

Kevin Schomacker

James Mansfield

Svetlana V Panasyuk

Charles R Lambert

Nikiforos Kollias

Pierre C Trepagnier

Edgar Neil Lewis

Michael E Leventon

Alexander Panasyuk

Brian H Tracey

M Leventen

John C Taffe

Alexander A Panasyuk

Creighton J Oyler

Michael Leventon

The invention is directed to methods and systems of hyperspectral and multispectral imaging of medical tissues. In particular, the invention is directed to new devices, tools and processes for the detection and evaluation of diseases and disorders such as, but not limited to diabetes and peripheral vascular disease, that incorporate hyperspectral or multispectral imaging.

Hyperspectral imaging in diabetes and peripheral vascular disease

A medical device is provided that comprises: (i) an expandable capsule that can be swallowed by a patient and positioned to a target tissue within the patient, (ii) an endoscope attached to the capsule for obtaining an image of the target tissue at a wavelength of interest, and (iii) a thin tube or wire configured to position the device to the target tissue. The thin tube or wire is expandable. The capsule can be swallowed in stages to position the device at different locations within the gastrointestinal tract. The thin tube or wire can deliver electromagnetic radiation for visualization of the target tissue. The thin tube or wire can provide a passage of a biopsy device for access to the target tissue. In some instances, the capsule comprises a band which rotates around the capsule to clean the capsule. In some instances, the capsule collects multispectral or hyperspectral information.

Device and method of balloon endoscopy

The invention is directed to methods and systems of hyperspectral and multispectral imaging of medical tissues. In particular, the invention is directed to new devices, tools and processes for the detection and evaluation of diseases and disorders such as, but not limited to diabetes and peripheral vascular disease and cancer, that incorporate hyperspectral or multispectral imaging.

Systems and methods for combining hyperspectral images with color images

This invention relates generally to an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment. The index map may also be a map of perfusion and/or metabolism of the tissue (reflecting oxygen delivery and oxygen extraction, obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging. This information aids treatment in prevention of diabetic foot ulceration and amputation and in treatment of tissue compromise to prevent tissue loss in other body regions.

Hyperspectral technology for assessing and treating diabetic foot and tissue disease

The invention comprises devices and methods for carrying quantities of materials preferably fluids. The device of the invention is preferably a wearable garment such as, preferably a vest or poncho, with one or more bladders or compartments adapted to hold a fluid. Preferably the garment comprises fluid connections between the bladders. The connections allow for the distributing the load over the carrier, which is preferably a person. The invention is designed to be inexpensive to manufacture, capable of easy manufacture in large numbers, and, if desired, disposable or repurposed. The device significantly enhances the ability of an individual to provide water or other fluids or materials to individuals or groups such as families. Preferably the invention allows for the transport of potable water from a supply point to the point of end use with minimal or no discomfort to the wearer. Preferably the invention supports the heating and/or cooling of the fluid or other applications, including use of building materials.

High volume individual fluid transport device

Wearable fluid-containing vest

Hyperspectral imaging of angiogenesis

The present invention provides a hyperspectral imaging system which demonstrates changes in tissue oxygen delivery, extraction and saturation during shock and resuscitation including an imaging apparatus for performing real-time or near real-time assessment and monitoring of shock, including hemorrhagic, hypovolemic, cardiogenic, neurogenic, septic or burn shock. The information provided by the hyperspectral measurement can deliver physiologic measurements that support early detection of shock and also provide information about likely outcomes.

Hyperspectral/multispectral imaging in determination, assessment and monitoring of systemic physiology and shock

This invention relates generally to an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment. The index map may also be a map of perfusion and/or metabolism of the tissue (reflecting oxygen delivery and oxygen extraction), obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging. This information aids treatment in prevention of diabetic foot ulceration and amputation and in treatment of tissue compromise to prevent tissue loss in other body regions.

Balloon probes, adapted for use in endoscopy and other medical procedures, are useful to obtain spectroscopic information reflected or emitted from a tissue of interest in the infrared spectral region. The information collected by the probe is useful in the diagnosis and treatment of disease. The invention also relates to methods utilizing these probes to analyze a surface of interest, in a minimally invasive manner, in connection with the diagnosis and treatment of disease.

Infrared endoscopic balloon probes

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Mary Ester, FL, United States of America

Michael J Hopmeier