Zoll Medical Corporation

Precision Therapeutics, Inc.

Michael J Gabrin

Gary A Freeman

Christopher L Swenglish

Sean McDonald

Anuja Chattopadhyay

Holly Gallion

Payal Nanavati

Stacey Brower

Shara Dawn Rice

A cardiac monitoring and treatment system includes a controller, a first wearable portion, and a second wearable portion separate from the first wearable portion. The first wearable portion includes an elongated strap configured to encircle a thoracic region of a patient, a plurality of ECG sensing electrodes disposed about the elongated strap, one or more receiving ports configured to receive one or more additional components including a treatment electrode and/or an additional sensor, and a plurality of conductive wires configured to couple the plurality of ECG sensing electrodes and the one or more receiving ports with the controller. The second wearable portion is configured to be worn over at least one shoulder of the patient and includes a wearable substrate, one or more treatment electrodes disposed on the wearable substrate, and at least one conductive wire configured to releasably connect the one or more treatment electrodes to the controller.

Modular garment for a wearable medical device

An ergonomic and unobtrusive cardiac monitoring and treatment device for continuous wear includes a band, ECG sensing electrodes and treatment electrodes configured to deliver an electrotherapy, one or more sensor ports for receiving one or more physiological sensors, and a controller for analyzing an ECG signal of a patient and causing a delivery of electro therapy. The band is configured to be worn about a thoracic region and has a vertical span of between about 1 to about 15 centimeters. The band is configured to be immobilized relative to a skin surface of the thoracic region of the patient by exerting one or more compression forces against the thoracic region. The device can include at least two separate wearable portions comprising a band portion including ECG sensing electrodes and/or other physiological sensors, and a second wearable portion optionally separable from the band portion, the second wearable portion including treatment electrodes.

The assays, methods, tools and systems discussed herein represent an improved and unified system for monitoring the progression of an individual patient malignancy. The assays, methods, tools and systems discussed herein represent an improved and unified system for monitoring and for identifying cellular and secreted markers, for screening cells to detect phenotypic and genotypic drift and for predicting chemotherapeutic response of patient tumor cells to at least one therapeutic agent. The assays, methods, tools and systems discussed herein also represent an improved and unified system for monitoring and for screening multiple pharmaceutical agents for efficacy and long term effect as to a specific patient.

Chemo-sensitivity assays using tumor cells exhibiting persistent phenotypic characteristics

Growing community of inventors

Pittsburgh, PA, United States of America

Michael J Gabrin