Motorola Corporation

Illumina Corporation

Motorola Mobility LLC

Other

Google Inc.

Google Technology Holdings LLC

Michael J Carney

Christopher P LaRosa

Christopher John Becker

Robert T Love

Weimin Xiao

Rapeepat Ratasuk

Stanley S Hong

Robert Ezra Langlois

James C Baker

Hongji Ren

Christopher P La Rosa

Kevin Wayne Bartig

Rico Otto

Olga Andreevna Souverneva

Amitabha Ghosh

Brian David Storm

Christopher P Larosa

Tracie Ann Schirtzinger

Fuyun Ling

Colin D Frank

Armin Werner Klomsdorf

Amitava Ghosh

Dale Gerard Schwent

Phillip D Rasky

Francisco Jose Garcia

Gregory M Agami

Steven H Goode

Thomas Peter Krauss

Anthony R Schooler

Robert S Trocke

Yun H Kim

Joseph F Cramer

Michael A Eberhardt

Ludovic Tancerel

Chris T Quanbeck

Jacobus De Beer

Partha Mukherjee

Hsu-lin Tsao

Daniel Joseph Tracy

Dave Steckl

Karthik Ramaswamy

Aaron Day

Come Raczy

Christopher J Becker

Methods, systems, and apparatuses, including computer programs, for performing incremental secondary analysis of nucleic acid sequence reads. The method can include (i) obtaining first data describing a plurality of first reads generated by a nucleic acid sequencing device during a first read interval, (ii) obtaining second data describing a plurality of second reads generated by the nucleic acid sequencing device during a second read interval that is performed after the first read interval, wherein while the second data is being obtained: (a) providing, by the nucleic acid sequencing device, the first data as an input to a mapping and alignment unit, (b) receiving, from the mapping and alignment unit, alignment results, and (c) storing the received alignment results, and, thereafter (iii) instructing the mapping and alignment unit to begin alignment of the second data representing the second plurality of reads to the reference sequence.

Incremental secondary analysis of nucleic acid sequences

Disclosed herein are systems and methods for performing secondary analyses of nucleotide sequencing data in a time-efficient manner. Some embodiments include performing a secondary analysis iteratively while sequence reads are generated by a sequencing system. Secondary analyses can encompass both alignment of sequence reads to a reference sequence (e.g., the human reference genome sequence) and utilization of this alignment to detect differences between a sample and the reference. Secondary analysis can enable detection of genetic differences, variant detection and genotyping, identification of single nucleotide polymorphisms (SNPs), small insertions and deletion (indels) and structural changes in the DNA, such as copy number variants (CNVs) and chromosomal rearrangements.

System and method for secondary analysis of nucleotide sequencing data

Implementations of the disclosure are directed to predicting structured illumination parameters for a particular point in time, space, and/or temperature using estimates of structured illumination parameters obtained from structured illumination images captured by a structured illumination system. Particular implementations are directed to predicting structured illumination frequency, phase, orientation, and/or modulation order parameters.

Predicting structured illumination parameters

Anesthesia character mask for children

Methods and apparatus for estimating time of arrival information associated with a wireless signal are disclosed. In an embodiment, a wireless device (), or any other suitable device or system, determines a channel type based on multiple occurrences of a reference signal () (e.g., determine if a channel is delay-spread or non-delay-spread based on a ratio of largest peak to a mean of other peaks). The wireless device () then selects a time of arrival generator (or) based on the channel type (e.g., use delay-spread estimator if ratio is below threshold, and use non-delay-spread estimator if ratio is above threshold). The wireless device then () estimates the time of arrival information using the selected time of arrival generator (or) (e.g., sum peaks from multiple occasions and then estimate for delay-spread or estimate the time of arrival from each occasion and then average for non-delay-spread).

Methods and apparatus for estimating time of arrival information associated with a wireless signal

A method and system synchronizes transmission of receive data over an asynchronous digital radio frequency interface in a wireless communication device. A timing accurate strobe (TAS) re-sampler generates, using a first timing strobe synchronized to a baseband modem clock, a second timing strobe synchronized to a radio frequency integrated circuit (RFIC) clock. The TAS re-sampler forwards the second timing strobe to the RFIC to trigger a collection of data samples and initiates a count of RFIC clock cycles. The RFIC sends the data samples to a baseband First In First Out (FIFO) buffer over the asynchronous interface. In response to the count reaching a pre-determined number of RFIC clock cycles corresponding to a fixed delay, the TAS re-sampler triggers a reading of data from the FIFO buffer. The baseband modem receives data corresponding to the collection of data samples after a fixed delay from generation of the first timing strobe.

Synchronizing receive data over a digital radio frequency (RF) interface

A wireless communication system () and method for providing high speed uplink packet access from user equipment () to a base station (). Each of the user equipment () and the base station () includes a transmitter (), a receiver (), and a controller () coupled to the transmitter and the receiver. Data packets are transmitted from the user equipment () to the base station (). Control information, corresponding to the data packets, is transmitted from the base station () to the user equipment (). The control information includes at least a control channel acknowledgement field in an absolute grant channel assigned to the user equipment (). The controller () of the user equipment () is configured to utilize the channelization code(s) in response to handoff and/or entering an active channel state.

System and method for downlink signaling for high speed uplink packet access

A wireless communication system () and method for providing high speed uplink packet access from user equipment () to a base station (). Each of the user equipment () and the base station () includes a transmitter (), a receiver (), and a controller () coupled to the transmitter and the receiver. Data packets are transmitted from the user equipment () to the base station (). Control information, corresponding to the data packets, is transmitted from the base station () to the user equipment (). The control information includes an absolute grant channel indicator. The controller () of the user equipment () is configured to disable an uplink transmission of the transmitter based on a indicator in the control information.

A communication unit is provided having a transmitter and a processor (). The processor () receives information () representative of a configuration of physical channels (). The processor () determines a scaling factor responsive to the information () and facilitates scaling a signal () provided by a combination of the channels utilizing the scaling factor. The scaled signal () is provided to the transmitter.

Method and system for scaling a multi-channel signal

A wireless communication system () and method for providing high speed uplink packet access from user equipment () to a base station (). Each of the user equipment () and the base station () includes a transmitter (), a receiver (), and a controller () coupled to the transmitter and the receiver. Data packets are transmitted from the user equipment () to the base station (). Control information, corresponding to the data packets, is transmitted from the base station () to the user equipment (). The control information includes an absolute grant channel indicator and/or channelization code(s) assigned to the user equipment (). The controller () of the user equipment () is configured to minimize a number of channelization code per scheduling active set cell to be monitored by the user equipment based on the absolute grant channel indicator and/or to utilize the channelization code(s) in response to handoff and/or entering an active channel state.

An apparatus for acquiring a pseudo-random (PN) sequence timing for a code division multiple access (CDMA) radiotelephone. A buffer stores samples of representations of at least one pilot signal. A correlator coupled to the buffer is operable to correlate at least a portion of the samples with a PN sequence at each of a plurality of different PN offsets to produce corresponding correlation energies. A controller coupled to the correlator interrupts the correlator as soon as the PN sequence at a particular PN offset produces a correlation energy at least equal to an energy threshold.

Method and apparatus for acquisition of a spread-spectrum signal

A method of activating a radiotelephone operable in a spread-spectrum multiple access radiotelephone system. A searcher receiver () is activated, and the searcher receiver () acquires a PN sequence timing of a pilot signal. At least one demodulation branch () is activated after activation of the searcher receiver (), and the demodulation branch synchronizes to the PN sequence timing of the selected pilot signal after the searcher receiver () has acquired the PN sequence timing.

Method of and apparatus for activating a spread-spectrum radiotelephone

A method () and a mobile station () for reporting multi-path signals based on a report window are described herein. The mobile station () may determine a distribution of a plurality of multi-path signals observed by a receiving unit () within the mobile station (). The mobile station () may determine a report window based on the distribution. Based on the report window, the mobile station () may report at least one of the plurality of multi-path signals.

Method and mobile station for reporting multi-path signals based on a report window

Growing community of inventors

Palatine, IL, United States of America

Michael J Carney