University of Minnesota

Michael J Annen

Peter W Carr

John Edward Morris

Michael C Flickinger

Michael J Robichaud

Christopher Dunlap

Colleen M Griffith

Alon V McCormick

Lifang Sun

Jason R Brown

Porous Zirconia particles of specific gravity of 2.5-3.5 g/cm.sup.3 and mean particle sizes of 30-400 .mu.m can be synthesized using oil emulsion methods from colloids and used for protein adsorption in stable expanded beds. Expanded beds of less than 1.0 settled bed height to diameter (approximately 10 ml bed volume) are stable at linear fluid velocities of at least about 100 cm/hour.

Protein adsorption by very dense porous zirconium oxide particles in

Porous zirconia particles of specific gravity of 2.5-3.5 g/cm.sup.3 and mean particle sizes of 30-400 .mu.m can be synthesized using oil emulsion methods from colloids and used for protein adsorption in stable expanded beds. Expanded beds of less than 1.0 settled bed height to diameter (approximately 10 ml bed volume) are stable at linear fluid velocities of at least about 100 cm/hour.

The present invention provides improved methods for the preparation of porous inorganic particles. The methods involve combining an aqueous sol containing a colloidal dispersion of inorganic particles with a polymerizable organic material, polymerizing this material, and thereby forming aggregates of colloidal particles and polymer.

Synthesis of porous inorganic particles by polymerization-induced

Growing community of inventors

Monroeville, PA, United States of America

Michael J Annen