Endotex Interventional Systems, Inc.

Gore Enterprise Holdings, Inc.

Boston Scientific Scimed, Inc.

Novostent Corporation

Articulinx, Inc.

Neoseed Technology LLC

Other

Arteria Medical Science, Inc.

Ethicon, Gmbh

Duke University

Corvascular, Inc.

Boston Scientific Cupertino Corporation

Arteria Medical Sciences, Inc.

Baff LLC

Boston Scientific Corporation

Michael Hogendijk

Farhad Khosravi

Mark C Bates

John C Spiridigliozzi

Juan C Parodi

Janine C Robinson

Amir Abolfathi

Himanshu N Patel

Michael Peter Ross

Gerald Dorros

Michael P Wallace

Michael R Ross

Thomas C Green

Gavin P Wallace

Claudio Javier Schönholz

David Deaton

Michael Austin Dotsey

Ryan Boucher

Eric W Leopold

Mark Christopher Bates

Todd Thompson

Hugh L Narciso, Jr

Gerald Ray Martin

Jayson Delos Santos

Nicola A Pisano

Mark H Wholey

David White

John Peckham

Claudio Javier Schoenholz

Juan Carlos Parodi

Richard S Stack

Isidro Matias Gandionco

Miles D Alexander

Francis G Duhaylongsod

Keith Seiler

Krishna Rocha-Singh

Edo Ziring

Tim Ngoc Huynh

Christopher K Huynh

Troy Chapman

Yuri Belman

Larry DeSoto

Harry R Phillips, Iii

Paul M Paspa

Mary Ann Parker, Legal Representative

Ryan P Boucher

Alexander Miles

Methods and apparatuses for removing material (e.g., clot) from within a body, including inverting thrombectomy apparatuses. These methods and apparatuses may include methods and apparatuses for reusing portion of the devices, method and apparatuses for loading and reloading the inverting thrombectomy apparatuses, and methods and apparatuses for improving and enhancing the ability of the inverting thrombectomy apparatuses to remove clot. In particular, described herein are expandable scraper devices that may be used in conjunction with the inverting thrombectomy apparatuses descried herein, or on their own.

Thrombectomy apparatuses

Thrombectomy methods

Bone marrow harvesting devices and methods of use for harvesting bone marrow from a biological source of bone marrow are provided that promote ease of use, and reduce patient pain and potential trauma to harvested bone marrow, wherein an exemplary bone marrow harvesting device includes an elongated shaft comprising a distal region, a proximal region, and a lumen extending therebetween, the distal region comprising a plurality of through-wall apertures in fluid communication with the lumen; and an expandable member disposed along the distal region thereof and configured to transition between a collapsed state and an expanded state for vibrating to disrupt the bone marrow. Methods of using the inventive bone marrow harvesting device to provide more efficient bone marrow disruption, improve the efficiency of bone marrow aspiration, and increase the quantity of bone marrow harvested in a single procedure are also provided.

Bone marrow harvesting device

An implantable vascular prosthesis is provided for use in a wide range of applications wherein at least first and second helical sections having alternating directions of rotation are coupled to one another. The prosthesis is configured to conform to a vessel wall without substantially remodeling the vessel, and permits accurate deployment in a vessel without shifting or foreshortening.

Vascular prosthesis and methods of use

Methods and apparatuses for treatment of various joint conditions include a device inserted into a joint space. During delivery, the profile of the device is constrained in at least one dimension to minimize invasive impact on tissue and/or bone. The device may be restrained for implantation by a thread or a rigid elongate member. After insertion, the device may expand at the implantation site.

Disc-shaped orthopedic devices

Devices and treatments for various joint conditions include a resilient elongate orthopedic device inserted into a joint space using a suture. The suture is passed through the joint space and used to pull the orthopedic device into the joint space. The suture may be using a percutaneously inserted needle or other type of needle-based delivery instrument. The resilient elongate orthopedic device may be restrained to a reduced profile that permits minimally invasive implantation, but assume an enlarged profile when positioned at an implantation site.

Suture-based orthopedic joint devices

Vascular prosthesis with alternating helical sections

Suture-based orthopedic joint device delivery methods

Disc-based orthopedic devices

An emboli filtration apparatus is provided including a guide wire having a filter element captured thereon, so that the guide wire is free to rotate and translate while the filter element remains stationary. The apparatus allows for movement and rotation of the guide wire as devices are advanced over it to treat occlusive disease, substantially without dislodging the filter element. In a preferred embodiment, the guide wire includes a proximal stop configured to reposition the filter element during a medical procedure without having to remove or insert additional interventional devices.

Emboli filtration system and methods of use

A prosthesis is provided for treating aneurysms, occlusive disease of vessels and body organs, and arterio-venous fistulas, occurring in single and bifurcated lumens. The prosthesis comprises an expandable coiled sheet portion having a biocompatible graft, either a sheet or tube, affixed thereto along part or all of the circumference of the coiled sheet portion. The prosthesis has a small delivery profile, making it suitable for use in a variety of body vessels. Methods of making and deploying the prosthesis in single and bifurcated lumens are also provided.

Coiled sheet graft for single and bifurcated lumens and methods of making and use

Embolic protection and plaque removal apparatus and methods are provided wherein an aspiration device aspirates, filters and reperfuses blood using a closed fluid circuit having a bi-directional working lumen. The plaque removal device includes a plurality of self-expanding cutting elements that form a cage that self-centers within the blood vessel to reduce the risk of trauma to the vessel lining.

Embolic protection and plaque removal system with closed circuit aspiration and filtering

Methods and apparatus are provided for removing emboli during an angioplasty, stenting or surgical procedure comprising a catheter having an occlusion element, an aspiration lumen, and a blood outlet port in communication with the lumen, a guide wire having a balloon, a venous return sheath with a blood inlet port, and tubing that couples the blood outlet port to the blood inlet port. Apparatus is also provided for occluding the external carotid artery to prevent reversal of flow into the internal carotid artery. The pressure differential between the artery and the vein provides reverse flow through the artery, thereby flushing emboli. A blood filter may optionally be included in-line with the tubing to filter emboli from blood reperfused into the patient.

Apparatus and methods for reducing embolization during treatment of carotid artery disease

Growing community of inventors

Palo Alto, CA, United States of America

Michael Hogendijk