Schering Aktiengesellschaft

Michael-Harold Town

Walter Elger

Werner Skuballa

Helmut Vorbrueggen

Bernd Raduechel

Olaf Loge

Norbert Schwarz

Helmut Vorbruggen

Ekkehard Schillinger

Bernd Raduchel

Martin Haberey

Gerda Mannesmann

Bob Nieuweboer

Claus-Steffen Sturzebecher

VorbruHelmut

5-fluorocarbacyclin derivatives of the Formula I ##STR1## wherein R.sub.1 is CH.sub.2 OH or

5-fluorocarbacyclins, their preparation and pharmaceutical use

9-fluoroprostane derivatives of Formula I ##STR1## wherein R.sub.1 is CH.sub.2 OH or ##STR2## wherein R.sub.2 is hydrogen, alkyl, cycloalkyl, aryl, or a heterocyclic residue; or R.sub.1 is the residue ##STR3## wherein R.sub.3 is an acid residue or R.sub.2 and A is --CH.sub.2 --CH.sub.2 -- or cis--CH.dbd.CH--,

9-fluoroprostaglandin derivatives, their preparation and use as

Compounds of Formula I ##STR1## wherein R.sub.1 is a prostaglandin or prostacyclin residue;

Prostaglandins and prostacyclins, process for their preparation and

Carbacyclin esters of Formula I ##STR1## wherein R.sub.1 is an unsubstituted or substituted aromatic residue,

Novel carbacyclin esters, process for the preparation thereof, and their

.DELTA..sup.8,9 -Prostane derivatives of Formula I ##STR1## wherein R.sub.1 is CH.sub.2 OH or ##STR2## wherein R.sub.2 is hydrogen, alkyl, cycloalkyl, aryl, or a heterocyclic residue; or R.sub.1 is ##STR3## wherein R.sub.3 is an acid residue or R.sub.2 ; A is --CH.sub.2 --CH.sub.2 -- or cis--CH.dbd.CH;

.DELTA..sup.8,9 -Prostaglandin derivatives, their preparation and use as

Prostaglandins and prostacyclins, processer for their preparation and

9-Fluoroprostane derivatives of Formula I ##STR1## wherein R.sub.1 is CH.sub.2 OH or ##STR2## wherein R.sub.2 is hydrogen, alkyl, cycloalkyl, aryl, or a heterocyclic residue; or R.sub.1 is the residue ##STR3## wherein R.sub.3 is an acid residue or R.sub.2 and A is --CH.sub.2 --CH.sub.2 -- or cis--CH.dbd.CH--,

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Berlin, Germany

Michael-Harold Town