Bayer Aktiengesellschaft

Bayer Pharma Aktiengesellschaft

Bayer Cropscience Ag

Bayer Cropscience Nv

Michael Harnau

Klaus Ochmann

Nils Burkhardt

Franco Fois

Andreas Schade

Bernd Kalthof

Georg Schmidt

Karl-Hermann Koeching

Mike Küster

Linn Schneider

Piet Soetaert

Bastian Budde

Martin Leube

A dispensing device includes a housing having at least one pressure chamber, having a supply opening for the supply of liquid into the pressure chamber and having a multiplicity of conduits between the pressure chamber and an external side of the housing, there being situated in each of the conduits a tube, the first end of which protrudes into the pressure chamber and the second end of which protrudes out of the housing on the external side.

Metering device

A method and a system for rapid kinetic fluorescence measurement in high-throughput screening with high time-resolution includes providing a microtiter plate having a transparent base and multiple assay wells, a dispensing system arranged above the microtiter plate for simultaneously adding liquid into multiple assay wells, an illumination system beneath the microtiter plate for illuminating the multiple assay wells simultaneously through the transparent base, a detection system for detecting electromagnetic radiation from the multiple assay wells simultaneously through the transparent base, adding 0.3-300 &#x3bc;l of liquid per assay well from the dispensing system into the multiple assay wells, illuminating the multiple assay wells simultaneously through the transparent base using the illumination system before or from the time point of the start of the addition, detecting the electromagnetic radiation from the multiple assay wells simultaneously at a time interval of 1-1000 ms between individual measurement points.

Method and system for taking measurements in a high-throughput screening with high time resolution

The invention relates to a device () and a method for determining the action of active ingredients on nematodes and other organisms in aqueous tests. The device () according to the invention comprises a holder () for a cell culture plate () having multiple wells () in which the nematodes can be filled with the active ingredients, said cell culture plate () having a bottom side (), a top side () and also side walls extending between bottom side () and top side (), a camera () which is used to record images of preferably the bottom side () of the cell culture plate (), a lighting mechanism () having at least a first light source () which illuminates the cell culture plate (), there being arranged between the first light source () and a first side wall () of the cell culture plate () in the installed state a first optical unit which directs the light of the first light source () through the first side wall () in the direction of the bottom side () of the cell culture plate (). The method according to the invention makes it possible to simultaneously investigate many active ingredients within a very short time.

Device and method for determining the action of active ingredients on nematodes and other organisms in aqueous tests

Methods, kits and compositions of matter are provided which allow amplification of nucleic acid or interest or DNA of interest, comprising the steps of isolating template nucleic acid or DNA from a biological sample using an alkaline extraction solution and directly adding the extract to a reaction mixture, under conditions to amplify the nucleic acids, wherein the isolated template nucleic acid or DNA in the alkaline extraction solution is not diluted or not neutralized prior to the addition to the reaction mixture.

Methods, compositions and devices for amplification of nucleic acids

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Leichlingen, Germany

Michael Harnau