Eth Zurich

Unversität Zürich

Csem Centre Suisse D'electronique Et De Microtechnique Sa

Eth Zurich, Eth Transfer

Cytosurge Ag

Michael Gabi

Janos Vörös

Tomaso Zambelli

Pascal Behr

Julia Vorholt-Zambelli

Daniel Eberli

Janos Voeroes

Stefan Pablo Doerig

Philipp Stiefel

Thomaso Zambelli

Lukas Hefermehl

Alexandre Lar-Magnac

André Meister

Jérôme Polesel-Maris

The invention relates to a method for spatially manipulating a microscopic object including providing a cantilever () having a tip with an opening () and a microchannel () extending through the cantilever () in its longitudinal direction. A suspension means is provided for holding the cantilever () and spatially moving the cantilever along a predetermined spatial path. A pressurizing means is provided for applying a predetermined pressure to the microchannel () and the cantilever () is moved with its tip to the microscopic object to be spatially manipulated. At least a part of the microscopic object is picked up with said cantilever () by reducing the pressure within the microchannel () relative to the pressure outside the tip of the cantilever (). The microscopic object is then moved along a predetermined spatial path by means of the cantilever ().

Method for spatially manipulating a microscopic object and device for conducting said method

The invention relates to a probe arrangement () for exchanging in a controllable way liquids with micro-sized samples of material like biological cells, especially in connection with an scanning probe microscope, said probe arrangement () comprising a probe holder () with at least one embedded first channel () and a cantilever () with at least one embedded second channel () and being provided to be attached to said probe holder () in a way that at least one aperture () of the first channel () is connected to at least one aperture () of the second channel () in a way that permits the liquid-tight transfer of a liquid between said first and second channels (). A safe and easy use of the probe arrangement is achieved by having the cantilever () permanently attached to said probe holder () to form a prefabricated probe unit ().

Probe arrangement for exchanging in a controllable way liquids with micro-sized samples of material like biological cells

A medical device is disclosed, which comprises a functional unit (C) for permanent or temporary placement in the urogenital tract of a human or animal body. The functional unit has at least one electrically conducting portion. A power source (G) supplies a current to the electrically conducting portion after placement of the functional unit in the urogenital tract. In this manner, the growth of bacteria on the functional unit can be reduced.

Prevention of bacterial adherence and growth in an urological implant

A probe arrangement with a probe for local electrophysiological analysis of cells () such as patch-clamp techniques for use with atomic force microscopy, has a probe with a cantilever arm () connected to a probe holder (). The probe has a probe tip () at a probing end () of the cantilever arm () and a fluid channel () in the cantilever arm () connecting a probe tip aperture () with a fluid reservoir () via a duct (). The fluid channel (), the duct () and the fluid reservoir () are adapted to be filled with a fluid solution () enabling ion transport for electrophysiological analysis. A first electrode () for electrophysiological analysis is placed in the fluid reservoir () and/or in the duct () and/or in the fluid channel ().

Probe arrangement

Growing community of inventors

Zurich, Switzerland

Michael Gabi