John Wyeth Brother, Limited

Pfizer Corporation

Michael G Wyllie

Terence J Ward

Alan C White

John Frederick Cavalla

George M Milne, Jr

Martyn D Wood

A method of relieving erectile impotence in a human male. The method comprises administering to the male an erectile impotence relieving amount of a compound selected from the group consisting of U.K. 52,046, Amlodipine, Doxazosin and the pharmaceutically acceptable acid addition salts thereof.

Method of treating impotence

This invention provides a method for preventing the development of hypertension in a non-hypertension animal, including a human, having an elevated natriuretic hormone level, which comprises administering to said animal an amount of indoramin or a pharmaceutically acceptable salt thereof effective to lower the natriuretic hormone level.

Method for prevention of hypertension

2,3,4,10-Tetrahydro-3,3-dimethyl-10-phenylpyrimido[1,2-a]indol-10-ol and the pharmaceutically acceptable acid addition salts thereof are useful in treatment or preventing obesity in mammals. The compounds may be administered in pharmaceutical compositions, optionally with one or more vitamins.

Anti-obesity agents

Treating cerebrovascular disorders characterized by poor oxygenation with 3-[2-C benzamide-1-piperidyl) ethyl] indole.

Method for treatment of cerebrovascular disorders

Xanthine derivatives are provided which exhibit psychotropic activity in that they inhibit 5-hydroxytryptamine reuptake in vitro and are indicated for antidepressive use.

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Maidenhead, United Kingdom

Michael G Wyllie