Yale University

Access Scientific, LLC

Vascular Insights LLC

Covidien Ag

Merit Medical Systems, Inc.

Contramed, LLC

Other

A.v. Medical Technologies Ltd

Empress Medical, Inc.

Smiths Medical Asd, Inc.

Cantramed, LLC

Tal, Michael G.

Michael G Tal

John P Marano, Jr

Janelle Anderson

Robert A Rabiner

Oleg Shikhman

Patrick N Gutelius

Benjamin K Yaffe

Mark James DeBisschop

William J McCreight

Richard M Braga

Brett Haarala

Christopher V Rainieri

Ilan Carmel

John P Marano

Steven F Bierman

Joshua T Druker

Michael Francis Wei

Stanley O Thompson

John Lapetina

James R Flom

Pasquale Patrizio

Carl Gandarillas

Gilad Magnazi

Josef Shahrur

Chris Labak

Robert Yuen Lee Ang

Aaron Abroff

Mark J Debisschop

Double-lumen infusion catheter including: a shaft having proximal section, distal section, and intermediate section therebetween; first and second lumens extending along a length of the shaft and having arc shaped wall therebetween; and an inflatable member provided distally to intermediate section, and over the distal section. First lumen has cross section larger than cross section of second lumen and is configured to receive a guidewire therethrough and allow fluid flow via an unobstructed portion of first lumen. Unobstructed portion is formed along guidewire outer surface, between guidewire outer surface and inner wall of first lumen, and extends from an inlet at proximal end of intermediate section to an outlet at distal end of intermediate section. First lumen is narrowed to approximate a first diameter in shaft proximal and distal sections, and is widened to approximate a second diameter greater than first diameter in the shaft intermediate section.

Infusion catheters and related systems and methods

A wire for use with a vascular treatment device may have a proximal end, a distal end, and a main shaft extending therebetween. The distal end may have a distal free end and a first segment. The first segment may extend from the main shaft and may be biased to a first included angle that is defined between the main shaft and the first segment and less than 180 degrees.

Wire and device for vascular treatment

A catheter is provided including a first lumen and a second lumen. A first member is disposed for relative movement within the first lumen and defines a cavity, A second member is disposed for relative movement within the second lumen. The cavity of the first member is configured for disposal of the second member. The catheter may include an elongated tubular body that includes the first lumen and the second lumen. The first member may have a distal portion that extends beyond the distal end of the body. The distal portion may include the cavity. The cavity may be defined by a member lumen. The first and second members may include tubular stylettes. The second member may include a guidewire.

Catheter insertion apparatus

A method for treating a tumor at least partially within an organ in a subject's body. The method comprises volumetrically compressing the tumor to increase a pressure within the tumor above a threshold level to cause ischemia of the tumor; and maintaining the pressure above the threshold level for a period sufficient to cause necrosis in the tumor. The method may include passing a tension member within the organ around a predetermined volumetric region encompassing at least a portion of the tumor. The method may include tightening the tension member to cause compression of the volumetric region, thereby directly increasing a pressure within the tumor. The method may include maintaining the increased pressure such that most or all tissues of the tumor undergo ischemia and/or necrosis resulting directly from the compression caused by the tightened tension member.

Causing ischemia in tumors

Disclosed are an apparatus and method for forming a passage extending along a plane crossing an organ's volumetric region from an entry point to an opposing exit point at a surface of the organ, and for passing a tension member around the volumetric region by pulling the tension member from the exit point to the entry point through the passage. The apparatus can include a rigid outer tube with a tip for penetrating the organ and reach a penetration depth; an inner needle with an elastic body configured to pass straightened through the outer tube lumen and to partially protrude and voluntarily flex to a curved form greater than the diameter of the volumetric region; and a tension member passer with a pulling portion for engaging with a portion of the tension member and for pulling the tension member when withdrawn.

Device and method for passing tension member around tissue mass

A percutaneous transluminal angioplasty (PTA) catheter may be configured to perform vein expansion and occlusion. A infusion port located proximal to the occlusion feature can be used to inject contrast enhancement agent as well as other substances. The catheter can be used especially advantageously in vascular regions associated with hemodialysis access.

Disrupting fibrin sheath from a host blood vessel and visualization thereof

An access device places a medical article within a body space of a patient. The device has a needle section that includes an elongated body and a needle hub. The device further includes a dilator portion that has a dilator and a dilator hub. The dilator is coaxially disposed and slideable over the elongated body of the needle section. The device further includes a sheath section that has a sheath and a sheath hub. The sheath is coaxially disposed and slideable over the dilator. The device further includes a first locking mechanism operably disposed between the needle hub and the dilator hub to inhibit at least unintentional axial movement between the needle section and the dilator portion and a second locking mechanism operably disposed between the dilator hub and the sheath hub to inhibit at least unintentional axial movement between the dilator portion and the sheath section.

Access device

An apparatus for performing a vascular treatment includes an intraluminal member that is controllingly moved during the vascular treatment. The intraluminal member of the vascular treatment device can be connected to a motor. The intraluminal member may be configured to retain endothelium during the vascular treatment procedure.

Vascular treatment devices and methods

A catheter is provided including a first lumen and a second lumen. A first member is disposed for relative movement within the first lumen and defines a cavity. A second member is disposed for relative movement within the second lumen. The cavity of the first member is configured for disposal of the second member. The catheter may include an elongated tubular body that includes the first lumen and the second lumen. The first member may have a distal portion that extends beyond the distal end of the body. The distal portion may include the cavity. The cavity may be defined by a member lumen. The first and second members may include tubular stylettes. The second member may include a guidewire.

An intravascular catheter may include a distal end for insertion and a proximal end. The distal end for insertion may terminate with a tip. It may define at least two openings, of which one is proximal-most in the distal end. The distal tip may include a first radiopaque marker that is discretely positioned at the proximal-most opening and radiographically distinguishes the proximal-most opening from the rest of the distal end. The distal tip may also include a second radiopaque marker that marks the tip.

Intravascular catheter with positioning markers and method of placement

An apparatus for performing a vascular treatment. In some embodiments, the apparatus comprises a vascular therapy device comprising a vascular treatment device and a feeder. The vascular treatment device can connect to a wire configured for use in vascular treatment. The vascular treatment device can rotate the wire. The feeder can be configured for controller the longitudinal translation of the wire. The feeder and the vascular treatment device can be independently or combinedly controlled.

Sclerotherapy catheter with lumen having wire rotated by motor and simultaneous withdrawal from vein

An intraluminal member can be used to deliver an adhesive to a vein while causing the vein to spasm, thereby controlling adhesive migration and improving procedure efficacy.

Adhesive-based varicose vein treatment

An apparatus for performing a vascular treatment includes an intraluminal member that is controllingly moved during the vascular treatment. The intraluminal member of the vascular treatment device can be connected to a motor. The rotation direction of the intraluminal member can be reversed to reduce the incidence and duration of vein entanglement during a vascular ablation procedure. Reversal of direction could occur automatically, or in response to a sensor such as a load sensor provided as part of the motorized drive system.

Direction reversing vascular treatment device

Growing community of inventors

Woodbridge, CT, United States of America

Michael G Tal