Fuisz Technologies Ltd.

Michael G Raiden

Pradeepkumar P Sanghvi

Tushar K Misra

Satish V Kamath

Jeffery W Currington

John R Sisak

Mahendra Govind Pankhania

Scott J Szedlock

Djelila Mezaache

Barbara Montwill

Jeffrey W Currington

Pradeep P Sanghvi

The invention relates to compositions useful for making taste-masked oral dosage forms which can be easily processed and which disintegrate rapidly when placed in the mouth. The compositions include coated liquiflash particles and shearform floss particles. Tablets are preferred dosage forms.

Dosage forms containing taste masked active agents

The invention relates to compositions useful for making tablets which can be formed using conventional tableting machines and which disintegrate rapidly in the mouth with optional chewing. The compositions typically include shearform matrices which have been recrystallized using crystallization promoters.

Fast-dissolving comestible units formed under high-speed/high-pressure

A self-binding, glycerine-free tablettable composition has a saccharide carrier and the sugar alcohols sorbitol and xylitol.

Self-binding shearform compositions

The invention relates to compositions useful for making tablets which can be formed using conventional tableting machines and which disintegrate rapidly when placed in the mouth. The compositions typically include partially hygroscopic shearform matrices which may be recrystallized using crystallization promoters.

Shearform compositions made without added glycerine are disclosed. The compositions are self-binding and exhibit excellent cohesivity when used in tableting compositions. Typically, xylitol is incorporated into a feedstock which is flash-flow processed to form a self-binding shearform matrix.

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Fairfax Station, VA, United States of America

Michael G Raiden