The Procter Gamble Company

Emory University

The Proctor 'gamble Company

Altiris Therapeutics, Inc.

Other

Children's Healthcare of Atlanta, Inc.

Michael G Natchus

Biswanath De

Neil Gregory Almstead

Stanislaw Pikul

Dennis C Liotta

Yetunde Olabisi Taiwo

David Brian Guthrie

Menyan Cheng

Donald G Stein

Iqbal Sayeed

Mark Andrew Lockwood

Michael Philip Clark

Kelly Lynn McDow-Dunham

Lawrence J Wilson

George R Painter

Gregory R Bluemling

Thomas L Cupps

Ketan Desai

Hyunsuk Shim

Florence Fevrier Wagner

Michael P Clark

John Charles Van Rens

Randall Stryker Matthews

Yesim Altas Tahirovic

Matthew John Laufersweiler

Zhe Wang

Gideon Shapiro

James P Snyder

Rodney D Bush

David B Guthrie

Richard K Plemper

Aiming Sun

Roger Gunnard Bookland

Rimma Sandler Bradley

John Wiseman

Jane Far-Jine Djung

Richard Arrendale

Joshua Spector Tullis

Mark A Lockwood

Steven Karl Laughlin

Kelly Michelle Solinsky

Benjamin Eric Blass

Norman Eugene Ohler

Brandon C Doroh

Jason W Skudlarek

Tricia L Johnson

Christopher MacNevin

Simona Jurczyk

Paul Mitchell Hershberger

John M Wiseman

Katherine King Mieling

John M Ndungu

Jeong-Joong Yoon

Cynthia Monesa Crago Clark

Christopher Thomas Wahl

Serdar Kurtkaya

Iestyn Lewis

Lawrence Wilson

Richard F Arrendale

Dennis Liotta

Christopher Macnevin

This disclosure relates to progesterone derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation resulting from traumatic brain injury or stroke.

Progesterone analogs and uses related thereto

This disclosure relates to progesterone phosphate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.

Progesterone phosphate analogs and uses related thereto

This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds.

N4-hydroxycytidine and derivatives and anti-viral uses related thereto

The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.

Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction

This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing inflammation such as those resulting from traumatic brain injury or stroke.

This disclosure relates to N4-hydroxycytidine derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment and prophylaxis of viral infections.

Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.

Steroid analogues for neuroprotection

Growing community of inventors

Alpharetta, GA, United States of America

Michael G Natchus