Roche Diagnostics Operations, Inc.

Boehringer Mannheim Gmbh

Roche Diagnostics Gmbh

Roche Diabetes Care, Inc.

Roche Molecular Systems, Inc.

Roche Operations Ltd.

Preh-werke Gmbh Co. Kg

F. Hoffmann-la Roche Ag

Michael Fritz

Thomas Weiss

Herbert Harttig

Frank Deck

Hans List

Heinz Kurt Macho

Gerhard Bienhaus

Claudio Immekus

Jurgen Schwab

Klaus-Dieter Sacherer

Thomas Walter

Dan Mosoiu

Edda Geisler

Hans-Juergen Kuhr

Richard Forster

Peter Vogel

David W Burke

Michael Marquant

Hans Lange

Rolf Lerch

Herbert Argauer

Detlef Thym

Volker Gerstle

Martin Frank

Udo Zapf

Chris Wilsey

Juergen Schwab

Christopher Douglas Wilsey

Joachim Steinbiss

Klaus Oswald

Peter Vetter

Andreas Rauscher

Helmut Rinkel

Alfred Schaffner

Georg Arras

Juergen Fick

Hans-Jürgen Kuhr

J&uuml;rgen Schwab

The present invention includes a system for withdrawing body fluids. The system includes a drive unit having a plunger which is moved from a resting position into a lancing position in order to carry out a lancing process and a lancing unit containing a lancet with a needle. The plunger and lancet are coupled together by a form fit in order to carry out a lancing process. The invention additionally concerns a method for temporarily extending a needle from a device for withdrawing body fluid as well as a lancing unit that can be attached to the drive unit.

System for withdrawing blood

The invention concerns lancets with a lancet needle, the tip of the lancet needle being embedded in an elastic material. Furthermore the invention concerns lancets where the tip of the lancet needle is surrounded by a hollow body which partially consists of an elastic material that can be pierced by the tip of the lancet needle during the lancing process and which reseals the tip of the lancet needle in the hollow body when it is retracted. In addition the invention concerns a lancet magazine in which the lancets are accommodated in individual chambers, each chamber having an opening through which the tip of the lancet needle can pass, which is sealed by an elastic material. Finally the invention concerns the use of an elastic material as a component of a lancet or a lancet magazine to maintain the sterility of at least the tip of a lancet needle in the unused state and to hygienically protect at least the tip of a lancet needle in the used state.

Blood lancet with hygienic tip protection

The invention concerns an analytical device containing a lancet comprising a lancet needle and a lancet body, the lancet needle movable relative to the lancet body and the lancet body composed, in the area of the tip of the lancet needle, of an elastic material in which the tip of the lancet needle is embedded, and an analytical test element connected to the lancet body. The invention also concerns an analytical device containing a lancet comprising a lancet needle and a lancet body in the form of a hollow body in the area of the tip of the lancet needle and surrounds the tip of the lancet needle, the lancet needle movable relative to the lancet body and the hollow body composed at least partially of an elastic material, and an analytical test element connected to the lancet body. The invention concerns a process for manufacturing an analytical device.

Analytical device with lancet and test element

The invention concerns an analytical device containing a lancet comprising a lancet needle and a lancet body, the lancet needle being movable relative to the lancet body and the lancet body being composed, at least in the area of the tip of the lancet needle, of an elastic material in which the tip of the lancet needle is embedded, and an analytical test element which is permanently connected to the lancet body. In addition the invention concerns an analytical device containing a lancet comprising a lancet needle and a lancet body which is in the form of a hollow body in the area of the tip of the lancet needle and surrounds the tip of the lancet needle, the lancet needle being movable relative to the lancet body and the hollow body being composed at least partially of an elastic material, and an analytical test element which is permanently connected to the lancet body. Finally the invention concerns a process for manufacturing such an analytical device.

A test strip having a small sample-receiving chamber on the order of less than 1 microliter. The inventive test strip includes a reagent layer that extends across the width of the test strip and also extends to the sample-receiving end, such that the edges of the reagent layer are aligned with the side and dose receiving edges of the test strip. The hydrophilic reagent extending to the dosing edge of the strip promotes wicking of the sample into the test strip. The end and side edges of the reagent layer are preferably formed as part of a cutting process that forms individual test strips from a larger web, which results in a smooth and thin reagent layer with a uniform thickness, substantially covering the entire floor of the sample-receiving chamber. The inventive mass production process helps improve the reproducibility of the quantity, location, thickness and other properties of the reagent layer, which in turn improves the accuracy of the test result.

Reagent stripe for test strip

A process and closure arrangement is provided for isolating purified biological material. The process includes placing biological materials in separate lysis vessels, adding lysis liquids to the biological materials in the lysis vessels, and transferring the liquids in the lysis vessels into a matrix unit. The liquids in the matrix vessels of the matrix unit are extracted through outlet openings during which the liquids flow through matrices and the matrix unit is placed on a collecting unit with collecting vessels which are arranged such that at least the outlet openings of the matrix vessels extend into the collecting vessels. The matrix vessels are with elution fluid and elution fluids from the matrix vessels are extracted through their outlet openings during which the elution fluids flow through the matrices and the elution fluids which are enriched with biological material are collected in the collecting vessels.

System for providing biological materials

This invention relates to test element analysis system for the analytical investigation of body liquids. An evaluation instrument, pertaining to the system, comprises a storage container, where a plurality of test elements is held ready for use, a sample application position, where one test element at a time is brought into contact with the sample, a measuring device for the determination of a measurable variable characteristic for the analysis, and a transport device, by which one test element at a time is taken out of the test element storage container at the take out position and transported to the sample application position.

Test element analysis system

The present invention is directed to a pipette comprising mounting surfaces of different diameters for the use of disposable tips of different size, which permits easy discarding of the tips after use. Such pipettes can be used in manual and automatic pipetting systems.

Pipette for disposable tips of different size

A system for simple nucleic acid analysis is described in which the amplification space contains at least a part of the binding space. An additional improvement is achieved by the design of the binding or/and amplification space which is optionally surrounded by a heatable metal layer.

System for simple nucleic acid analysis

The production of pouch-shaped or pot-shaped parts is undertaken in two steps. In the first step, a film located above a die is pressed by a stamp into a cavity that reproduces the part and is subsequently pressed apart in the lower region of the cavity by deformation of the stamp in this region. The device has a rubber-like stamp that expands out on all sides once it has reached the bottom wall of the cavity and causes the film to conform to the shape of the cavity. The stamp is preferably designed in two parts, wherein a stamp insert is guided within a stamp guide and the stamp insert then has at least one deformable region. For removal of the formed film, provision is made that the die can be swung open.

Method and device for producing pouch-shaped or pot-shaped parts and use of the parts for accommodating samples or the like

Growing community of inventors

Biblis, Germany

Michael Fritz