Gruenenthal Gmbh

Gruenethal Gmbh

Michael Franz-Martin Engels

Stefan Schunk

Ruth Jostock

Melanie Reich

Tieno Germann

Sabine Hees

Klaus Schiene

Stefan Oberboersch

Thomas Christoph

Achim Kless

Jean De Vry

Edward Bijsterveld

Substituted sulfonamide derivatives, a process for their preparation, pharmaceutical compositions containing these compounds, and to the use of substituted sulfonamide derivatives in the treatment or inhibition of pain and/or various disorders or disease states.

Substituted sulfonamide compounds

Substituted sulfonamide compounds corresponding to formula I: processes for the preparation thereof, pharmaceutical compositions containing these compounds, and the use of such substituted sulfonamide compounds in pharmaceutical compositions for the treatment and/or inhibition of pain and other conditions at least partly mediated by the bradykinin 1 receptor.

Substituted disulfonamide compounds corresponding to formula I: In which R, R, R, R, R, R, R, R, R, R, R, R, a, b, s, t and A have defined meanings, pharmaceutical compositions containing one or more such compounds, processes for preparing such compounds, and a method of using such compounds for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin receptor 1 (BR1).

Substituted disulfonamide compounds

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Turnhout, Germany

Michael Franz-Martin Engels