Colgate Palmolive Company

Northwestern University

Rutgers, the State University of New Jersey

Michael Fitzgerald

Iraklis Pappas

Long Pan

Harsh Mahendra Trivedi

Donghui Wu

LaTonya Kilpatrick-Liverman

Hrebesh Molly Subhash

Shamim Alam Ansari

Jean-Francois Gaillard

Marco Alsina Corvalan

Michael Pacelli

Robert D'Ambrogio

Yun Xu

David F Suriano

Peter Hilliard, Jr

Lisa Manus

Shashank Vishwanath Potnis

Mehdi Javanmard

Carlo Daep

Ekta Makwana

Melissa Martinetti

Joseph Convery

Karthik Sambanthamoorthy

Matthew J Eibling

Zhongtian Lin

Jianye Sui

Salima Hammadi

Shamim Ansari

Described herein are methods, systems and devices for rapidly detecting biomarkers in a biological sample.

Methods, devices and systems for quantifying biomarkers

Described herein are oral care compositions comprising—in relevant part—an effective amount of inulin. Methods of making and using these compositions are also described.

Oral care compositions

The disclosure contains a method of quantifying and/or evaluating metal ions in a dentifrice, wherein the method comprises subjecting the dentifrice to X-ray absorption spectroscopy (XAS), and wherein the XAS is used to measure and/or evaluate the metal ions in the dentifrice. Also disclosed are methods of selecting and screening for dentifrices based upon the evaluation and quantification of their metal ion content.

Analytical methods using X-ray absorption spectroscopy for quantifying or evaluating metal ions in a dentifrice

An oral care evaluation process may include: illuminating soft oral tissue within an oral cavity with a light source emitting a spectrum of light which induces fluorescence in an organic compound; generating image data for an image of the soft oral tissue while illuminating the soft oral tissue, the image comprising a plurality of pixels; and evaluating oral hygiene using a programmable processor programmed to assess an attribute of each pixel of the image.

Oral care evaluation system and process

Disclosed herein is mucin-coated silica, compositions comprising the same, and methods of promoting the aggregation and/or clearance of oral bacteria using such compositions.

Mucin coated silica for bacterial aggregation

Analytical methods using x-ray absorption spectroscopy for quantifying or evaluating metal ions in a dentifrice

An oral care evaluation system may include: a light source configured to emit a spectrum of light which induces fluorescence in an organic compound, the light source illuminating soft oral tissue within an oral cavity; an image sensor receiving light generated by fluorescence of the organic compound on the soft oral tissue, the image sensor generating image data for an image of the oral tissue, the image comprising a plurality of pixels; and an image processor receiving the image data from the image sensor and programmed to evaluate oral hygiene of the soft oral tissue by assessing an attribute of each pixel in the image.

The disclosure provides an improved synthesis for a zinc-lysine complex having the formula [Zn(CHNO)Cl]Cl, in which a zinc compound selected from ZnO and ZnCl, is reacted with a lysine compound selected from lysine and lysine.HCl, in aqueous acid. The disclosure also provides oral care and personal care compositions comprising the complex prepared by the synthesis, and methods of using these complexes and compositions.

Low pH sysnthesis of zinc-lysine complex

A method of producing an anhydrous antiperspirant composition comprising (a) providing a mixture of at least one antiperspirant active including a metal salt, and an anhydrous carrier for the at least one antiperspirant active in which the at least one antiperspirant active is dissolved, the carrier comprising a eutectic mixture of at least one basic compound selected from a basic amide and a basic amine and at least one member chosen from a cation and zwitterion; and (b) heating the mixture to form a stabilized eutectic system of the at least one antiperspirant active and the anhydrous carrier, and wherein the at least one antiperspirant active, the at least one basic compound and the at least one member chosen from a cation and zwitterion form a ternary eutectic system.

Method of making an anhydrous liquid antiperspirant composition

An anhydrous liquid antiperspirant/deodorant composition comprising a carrier comprising a cation and/or zwitterion and a hydrogen bond donor, wherein an amount of carrier is greater than an amount of any other material in the composition, and an antiperspirant active. This represents a new delivery form for antiperspirant actives and/or deodorant actives.

Anhydrous liquid antiperspirant composition

A method of producing an anhydrous antiperspirant composition comprising (a) providing a mixture of at least one antiperspirant active including a metal salt, and an anhydrous carrier for the at least one antiperspirant active in which the at least one antiperspirant active is dissolved, the carrier comprising a eutectic mixture of at least one basic compound selected from a basic amide and a basic amine and at least one member chosen from a cation and zwitterion; and (b) heating the mixture to form a stabilized eutectic system of the at least one antiperspirant active and the anhydrous carrier. Also, an anhydrous antiperspirant composition.

An aqueous antiperspirant/deodorant composition comprising: (a) at least one active chosen from an antiperspirant active and a deodorant active, (b) a mixture comprising at least one basic compound chosen from a basic amide and a basic amine and a counterpart material for the basic amide and/or basic amine, and (c) at least 10 weight % water. Also, a method of manufacturing the composition.

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Oakhurst, NJ, United States of America

Michael Fitzgerald