Gruenenthal Gmbh

Michael Finkam

Bernhard Akteries

Bernd Sundermann

Helmut Heinrich Buschmann

Babette-Yvonne Koegel

Oswald K Zimmer

Joerg Holenz

Helmut Buschmann

Corinna Maul

Stephan Wnendt

Johannes Schneider

Werner Winter

Kai Zwingenberger

Horst R Boehlke

Thomas Kohnen

Substituted 3-phenylpiperidine compounds corresponding to Formula I in which R1 and R2 have the meanings defined in the specification, methods for preparing such compounds, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting various conditions, especially pain.

Substituted 3-phenylpiperidine compounds, their preparation and use

Substituted C-cyclohexylmethylamine derivatives, methods for the production thereof, pharmaceuticals containing said compounds, the use of substituted C-cyclohexylmethylamine derivatives for producing pharmaceuticals, and method of pain treatment using the pharmaceuticals.

Substituted C-cyclohexylmethylamine derivatives

A process for preparing 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol with high stereoselectivity and high yield by reacting 2-[(dimethylamino)methyl]-cyclohexanone in a Grignard reaction with a Grignard compound of 3-bromoanisole in a suitable solvent and in the presence of an inorganic lithium salt and an &#x3b1;,&#x3c9;-dialkoxyalkane.

Process for preparing 2-[(dimethylamino)-methyl]-1-(3-methoxyphenyl)cyclohexanol

A method for separating the diastereomer bases of 2-&lsqb;(dimethylamino)methyl&rsqb;-1-(3-methoxyphenyl)-cyclohexanol in which the separation of the diastereomer bases takes place through formation of a base hydrate.

Process for separating the diastereomeric bases of 2-&lsqb;(dimethylamino)methyl&rsqb;-1-(3-methoxyphenyl)-cylohexanol

Lactam derivatives as immunomodulating agents

A method of preparing (3-alkoxyphenyl)magnesium chlorides and the use thereof for reaction with certain carbonyl compounds are described.

Preparation and use of (3-alkoxy-phenyl) magnesium chlorides

Growing community of inventors

Aachen, Germany

Michael Finkam