Monsanto Company

Michael F McGrath

Robert J Collier

Gwen G Krivi

Ned R Siegel

Brent R Larsen

Claire E Kotts

Sharon D Ogden

John C Minnerly

The growth of milk-producing mammary parenchyma in a mammal can be significantly enhanced by administering to the mammal by intramammary infusion a substance having a mitogenic effect on mammary epithelial cells in said mammal. Good growth enhancement can be achieved using very small quantities of such substances, and in relatively short periods of time.

Method for enhancing growth of mammary parenchyma using a prostaglandin

Method for enhancing growth of mammary parenchyma

This invention relates to novel peptides having utility for promotion of growth and/or lactation in animals, to processes and DNA useful in production of such peptides, and to methods utilizing such peptides to promote growth or lactation in animals. In some embodiments, the invention is directed to peptides having bovine IGF-II biological activity, to production of such peptides, and to their use in effecting proliferation of certain cells (e.g. mammary epithelial or muscle) or in enhancing lactation in cattle or other animals.

DNA sequences encoding bovine growth factors

Growth factors

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Chesterfield, MO, United States of America

Michael F McGrath