The William M. Yarbrough Foundation

Orvance, LLC

Other

Quadsil, Inc.

Michael E Silver

Charles A Schryver

Ronald J Schutt

John Donald Blizzard

Joan McMahon

A method that includes the step of applying an isothiocyanate functional surfactant containing composition to a skin where the isothiocyanate functional surfactant containing composition includes an isothiocyanate functional surfactant where the protonated form of the surfactant includes the structure of formula (IA): wherein Rincludes the structure of formula (IIA), (IIIA), or (IVA), wherein X includes an integer ranging from approximately 0 to approximately 20, wherein Rcomprises a linear or branched aliphatic group containing approximately 8 to approximately 25 carbon atoms, and wherein Rcomprises an aliphatic or aromatic group containing approximately 1 to approximately 20 carbon atoms and at least one —N═C═S group.

Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use

A composition and a method of washing urushiol off a surface. The composition includes a first solely Csurfactant and a second solely Csurfactant that are each in a non-buffered composition and the composition is free of each of the following: (1) any nonylphenol ethoxylate, (2) any pharmaceutically active drug or prodrug, or (3) any salt that affects the functional characteristics of either of the first solely C12 surfactant or the second solely C12 surfactant, (4) any salt in granular form, and (5) any ethoxylate added as a separate component and not part of the non-ionic polyethylene glycol ether of a mixture of synthetic C12-C15 fatty alcohols with an average of 9 moles of ethylene oxide.

Detergent compositions for washing urushiol and methods of treating urushiol induced contact dermatitis

A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition. In one embodiment, the protonated form of the isothiocyanate functional surfactant is represented by the following chemical structure:

Method for treating rheumatoid arthritis

A detergent composition and a method of washing/cleaning urushiol at least partially, more typically substantially or completely off a surface of human skin or clothing. The detergent composition is typically a non-buffered composition that contains one or more Csurfactants, typically at least a sodium lauroyl sarcosinate and the detergent composition is typically free of one or more of (1) any nonylphenol ethoxylate; (2) any pharmaceutically active drug or prodrug; (3) any salt in an amount that affects the functional characteristics of either of the solely Csurfactants; (4) any salt in granular form; and/or (5) any ethoxylate that is a stand-alone ingredient.

Sodium lauroyl sarcosinate containing detergent compositions

A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease. In one embodiment, the protonated form of the isothiocyanate functional surfactant is represented by the following chemical structure:

Method for treating infectious diseases with isothiocyanate functional compounds

The present disclosure is generally directed toward a pontic material that is pliable and easily moldable, possesses a higher tear resistance to resist fragmenting and thus is long lasting, can be pigmented to achieve a good color match to adjacent teeth, and be fashioned into a pontic by the patient at home so as to free the orthodontist and their staff from having to do this purely aesthetic and time-consuming procedure. In addition, the pontic material of the present disclosure is typically permanently pliable so that an untrained person such as a patient would have unlimited time to make corrections to the shape of the material to obtain an aesthetically pleasing shape and typically do so without the use of tools or any specialized tools or equipment.

Uncured pontic material for orthodontic clear aligners or retainers

A formulation, including: (a) a first medicament, wherein the first medicament includes an isothiocyanate functional compound/surfactant; and (b) a second medicament, wherein the second medicament includes an antineoplastic agent, such as a cytotoxic antineoplastic agent and/or a targeted antineoplastic agent.

Isothiocyanate functional compounds augmented with secondary antineoplastic medicaments and associated methods for treating neoplasms

A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by benign prostatic hyperplasia, prostatitis, and/or prostate cancer. In a preferred embodiment, the protonated form of the isothiocyanate functional surfactant is represented by the following chemical structure:

Method for treating metastatic prostate cancer

A method that includes the step of engaging an orthodontic protection device with a surface within a person's mouth chosen from the group consisting of: a tooth surface; an orthodontic appliance affixed to the tooth surface and a combination of the tooth surface and the orthodontic appliance affixed to the tooth surface. The orthodontic protection device includes an extruded base material that includes an uncured, uncross-linked silicone high consistency rubber base and the extruded base material has at least one dry, powdered hydrophilic polymeric substance on a surface of the extruded base material.

Powder coated malleable hydrophobic orthodontic device shield

A hygienically packaged composition that includes a base layer of a thermoplastic film, a covering film layer that is a heat sealable or pressure sealable adhesive liner that covers the hygienically packaged composition where the hygienically packaged composition is a dental composition, a food composition, or a medicine. The covering film layer includes a stretched dimple in a portion of the covering film layer proximate the hygienically packaged composition thereunder the covering film layer. There is typically a heat or pressure seal around each hygienically packaged composition.

Temporary tooth repair/treatment composition and methods of use thereof

A method that includes the step of using a person's fingers to push a dental composition into engagement with a damaged tooth surface of a damaged tooth thereby adhering the dental composition to the damaged tooth surface and covering at least a portion of the damaged tooth surface. The dental composition includes a base material comprising at least one of the following compounds chosen from the group consisting of: a product consisting of one or more hydrocarbon-based waxes that may also include inorganic fillers and/or organic fillers; an uncured, uncrosslinked silicone high consistency rubber base; and a hydrophobic water insoluble solid material. The base material has a coating composition on one or more surface of the base material wherein the coating composition comprises: one or more desensitization ingredient and at least one dry, powdered hydrophilic polymeric substance.

A composition and a method of washing urushiol off the surface of human skin. The composition includes a first solely C12 surfactant and a second solely C12 surfactant that are each in a non-buffered composition and the composition is free of each of the following: (1) any nonylphenol ethoxylate, (2) any pharmaceutically active drug or prodrug, or (3) any salt that affects the functional characteristics of either of the solely C12 surfactants.

An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.

A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition. In one embodiment, the protonated form of the isothiocyanate functional surfactant is represented by the following chemical structure: 

Growing community of inventors

Lake City, MI, United States of America

Michael E Silver