Miles Inc.

Michael E Katz

David G Osterman

Richard D Connell

Robert D Dally

Rudolf H Hanko

Stephan Schneider

A class of compounds that suppress human T-lymphocyte proliferation is disclosed. The active compounds essentially contain at least the following structure: ##STR1##

2-oxoethyl derivatives as immunosuppressants

Compounds which suppress human T-lymphocyte proliferation are disclosed. The active compounds essentially contain at least the following structure: ##STR1##

Aminomethylene derivaties as immunosuppressants

Sulfonamide aminomethylene derivatives as immunosuppressants

Compounds which suppress human T-lymphocyte proliferation are disclosed. The active compounds essentially contain at least the following structure: ##STR1## wherein A, R.sup.1, R.sup.2, R.sup.3, n, X.sup.1 and Z are defined in the specification.

Growing community of inventors

Wallingford, CT, United States of America

Michael E Katz