Cocrystal Pharma, Inc.

Other

Emerald Biostructures, Incorporated

Michael David Feese

Irina C Jacobson

Sam S K Lee

Sam S Lee

Lance Joseph Stewart

Mark B Mixon

Sridhar Prasad

Sam Sk Lee

Provided herein are compounds of Formula A, B or C that can inhibit the replication of influenza viruses, reduce the amount of influenza viruses, and/or treat influenza.

Pyrrolo[2,3-B]pyridin derivatives as inhibitors of influenza virus replication

Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient a safe and effective amount of a compound represented by any of Formulas I-III, or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a safe and effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle. 

Pyrrolopyrimidine derivatives useful as inhibitors of influenza virus replication

The present invention provides, among other things, compounds represented by the general Formula I: (I) and pharmaceutically acceptable salts thereof, wherein L and A (and further substituents) are as defined in classes and subclasses herein and compositions (e.g., pharmaceutical compositions) comprising such compounds, which compounds are useful as inhibitors of hepatitis C virus polymerase, and thus are useful, for example, as medicaments for the treatment of HCV infection. 

Inhibitors of Hepatitis C virus polymerase

Inhibitors of hepatitis C virus polymerase

Coils for receiving or transmitting electromagnetic signals comprising a plurality of concurrently wound and fully or partially interpenetrating windings for which the resonance frequency can be varied over a broad range. The presently described embodiments provide for electromagnetic pickups for stringed musical instruments; however, it is appreciated that other embodiments providing for a wide variety of devices comprising pickup coil sensors are apparent. It is also apparent that a wide variety of devices are possible in which coils with concurrently wound and interpenetrating windings will serve as transmitting coils.

Pickup coil sensors and methods for adjusting frequency response characteristics of pickup coil sensors

This invention encompasses an apparatus for creating a database containing the results of distributed molecular replacement searches, which comprise data input system for inputting the results of distributed molecular replacement searches and related information and a database generator coupled to said data input system for receiving the results of distributed molecular replacement searches and related information and creating a database for storing the results of distributed molecular replacement searches and related information. The invention includes method of managing the invention of distributed molecular replacement searches.

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Seattle, WA, United States of America

Michael David Feese