Luminex Corporation

Rules-based Medicine, Inc.

Michael D Spain

James P Mapes

James W Jacobson

Harold N Baker

Ralph L McDade

Dominic Eisinger

Samuel T Labrie

Karri L Ballard

Methods and devices for diagnosing, monitoring, or determining obstructive uropathy or an associated disorder in a mammal are described. In particular, methods and devices for diagnosing, monitoring, or determining obstructive uropathy or an associated disorder using measured concentrations of a combination of three or more analytes in a test sample taken from the mammal are described.

Methods and devices for detecting obstructive uropathy and associated disorders

The invention relates to methods of characterizing autoimmune diseases by detecting and measuring at least one analyte using multiplexed assay systems. According to one embodiment, a target is detected and measured by different bead sets having different reactants. According to another approach the ratio of self-antigen to autoantibody is measured by exposing a sample suspected of containing self-antigen and autoantibody to a bead set associated with monoclonal antibody specific for the self-antigen and a bead set associated with the self-antigen.

Method for characterizing autoimmune disorders

The present invention relates to the substantial elimination of errors attributable to carryover microspheres, doublets, or misclassification of microsphere subsets. The present invention is based upon passing a sufficient minimum number microspheres through the flow analyzer during an assay run.

System and method for eliminating the effects of doublets and carryover

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Austin, TX, United States of America

Michael D Spain