Cornell Research Foundation Inc.

Incodema3d, LLC

Michael D Pinnisi

Jochen Buck

Lonny Levin

Leo Brizuela

Scott Volk

A three dimensional (3D) definition of a build piece, from which a build plan has been derived, is received. The computer system generates, based on the 3D definition, a processing plan that includes a plurality of robotic instructions to successively orient a build piece created by an additive manufacturing process into successive orientations. The computer system outputs the processing plan for use by a robotic controller.

Method for processing additively manufactured part by robotically moving medium inside part cavity

The present invention relates to a method of preventing or treating a disease caused by infection by a eukaryotic pathogen, wherein the method comprises administering an effective amount of a modulator of a eukaryotic pathogen's adenylyl cyclase. The invention also provides pharmaceutical compositions useful for preventing or treating a disease, with the compositions containing a therapeutically effective amount of a modulator of a eukaryotic pathogen's adenylyl cyclase. The invention also provides screening methods for identifying selective modulators of a eukaryotic pathogen's adenylyl cyclase that do not substantially modulate an adenylyl cyclase of the subject. The invention also provides methods for culturing eukaryotic pathogens and methods for inducing the pathogenic state in vitro.

Adenylyl cyclases as novel targets for the treatment of infection by eukaryotic pathogens

The present invention relates to a method of preventing or treating a disease caused by bacterial infection by administering an effective amount of a modulator of bacterial adenylyl cyclase. The invention also provides pharmaceutical compositions useful for preventing or treating a disease, with the compositions containing a therapeutically effective amount of a modulator of bacterial adenylyl cyclase. The invention also provides screening methods for identifying selective modulators of bacterial adenylyl cyclase that do not substantially modulate adenylyl cyclase of the subject. The invention also provides methods for culturing bacterial pathogens and methods for inducing the pathogenic state in vitro.

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Ithaca, NY, United States of America

Michael D Pinnisi