Veterinary Infectious Disease Organization

University of Saskatchewan

Michael D Parker

Lorne A Babiuk

Graham J Cox

Mark J Redmond

Mohammed K Ijaz

Nucleic acid sequences encoding the Bovine Coronavirus E2 (or BCV S) and E3 (or BCV HE) structural glycoproteins and methods of producing these proteins, including recombinant expression, e.g., in mammalian or insect cells, are provided. The E2 and E3 proteins or antigenic fragments thereof are useful components for Bovine Coronavirus vaccines and methods of treatment.

Recombinant bovine coronavirus E2 and E3 polypeptides and vaccines

Bovine coronavirus (BCV) E2 and E3 coding sequences and materials for producing the proteins E2 and E3 are provided. E2, E3, or antigenic fragments thereof are useful components for a BCV vaccine.

DNA encoding bovine coronavirus polypeptides E2 and E3

Assembled viral particles derived from rotavirus proteins are disclosed. The assembled particles include the inner capsid protein, VP6, in combination with either or both of the outer capsid proteins, VP4 and VP7. These assemblies can be used in vaccine compositions for the treatment and prevention of rotaviral disease.

Growing community of inventors

Saskatoon, Canada

Michael D Parker