Other

Asthmatx, Inc.

Avails Medical, Inc.

Vnus Medical Technologies, Inc.

Ethicon Endo-surgery, Inc.

Broncus Technologies, Inc.

Broncus Medical Inc.

Boston Scientific Scimed, Inc.

Hearten Medical

Ndo Surgical. Inc.

Tyco Healthcare Group LP

Cordynamix, Inc.

Surx, Inc.

Ams Research Corporation

Solarant Medical, Inc.

Michael D Laufer

Bryan E Loomas

Christopher James Danek

Gary S Kaplan

Thomas M Keast

Amos G Cruz

Michael J Biggs

Kelly M Shriner

Jeffrey Cerier

William Wizeman

Oren S Knopfmacher

Meike Herget

Brian Eugene Farley

August Estabrook

Frank W Ingle

Mark P Parker

Garry L Carter

Edmund J Roschak

Henky Wibowo

Jonathan O'Keefe

Richard Andrews

Freddy Abnousi

Neal H Marshall

Cary Cole

Michael Barenboym

Vincent A Puicci, Jr

David P Thompson

Arthur W Zikorus

Keith M Burger

Nitin K Rajan

Suresh K Wadhwani

Ram Chuttani

Glendon E French

Jeffrey J Christian

Payam Adlparvar

Bruce D Stambaugh

Dawn A Henderson

Douglas M Petty

Grace Y Schulz

Martin N Lee

Randall B Chinnock

Geoffrey H Willis

D Bommi Bommannan

Don Akira Tanaka

Randal B Chinnock

Edward J Nance

Hien V Nguyen

Thomas F Kordis

Donald A Tanaka

Gary Henry Miller

David C Auth

Jerry Jarrard

Timothy R Dalbec

Dave Haugaard

Noah D Webster

Tim R Dalbec

Tony R Brown

Jeremy S Laufer

H DuBose Montgomery

Thomas R Cygan

Jennifer Almy

Gary Yip

Robert J Laird

Vincent A Piucci, Jr

James M Davenport

Loren L Roy

Paul L Do

Brian J Mosel

Creighton T Buie

Ed Roschak

Eszter Deak

Suzanne Putney

Andrew H Theiss

Elizabeth Botbol Ponte

Joel D Cooper

Hien Nguyen

John Arthur Ross

Sanjay S Bagade

Hein Nguyen

Mark K Parker

Celina Yong

Octavio V Adame

William J Wizeman

Jeffrey C Cerier

Methods, devices, systems of resuscitating a patient including accessing an arterial vessel positioning a catheter into the arterial vessel advancing the catheter through the arterial vessel to position it below a vessel supplying blood to a heart and a brain expanding an expandable portion of the catheter to prevent blood from flowing past the expanded portion and infusing a substance retrograde into the artery within the arterial section between the heart and the expanded portion of the catheter.

Systems, devices and methods for resuscitation

Various devices, systems and methods for detecting the presence of β-lactam antibiotic hydrolyzing bacteria in a sample are disclosed. In one embodiment, a method of detecting the presence of β-lactam antibiotic hydrolyzing bacteria includes introducing the sample to a filter configured to capture bacteria in the sample; introducing a buffer solution to the bacteria captured on the filter surface, wherein the buffer solution comprises a β-lactamase substrate, a β-lactamase activator, and a lysing agent to lyse cells of the bacteria to release β-lactam antibiotic hydrolyzing enzymes; exposing a sensor having an electrical characteristic to a reaction mixture comprising the buffer solution and the β-lactam antibiotic hydrolyzing enzymes; and monitoring a change in the electrical characteristic of the sensor to detect the presence of the β-lactam antibiotic hydrolyzing bacteria in the sample originally introduced.

Devices, systems and methods to detect the presence of ß-lactam antibiotic hydrolyzing bacteria in a sample

Various devices, systems and methods of detecting a susceptibility of one or more infectious agents to one or more anti-infectives are described herein. In one embodiment, a method of detecting the susceptibility of the infectious agents to the anti-infectives involves introducing a sample comprising the infectious agents to a filter comprising a filter surface. The filter surface can be configured to capture the infectious agents in the sample. The method can also involve introducing a solution to the filter surface such that the solution is in fluid communication with the infectious agents captured on the filter surface. The solution can comprise nutrients and one or more anti-infectives. The method can further involve monitoring an oxidation reduction potential (ORP) of the solution using one or more parameter analyzers coupled to a sensor currently in fluid communication with the solution to assess the susceptibility of the infectious agents to the anti-infectives.

Apparatus, systems, and methods for determining susceptibility of microorganisms to anti-infectives

Various methods, devices, and systems for determining the concentration of microorganisms in a sample and determining the susceptibility of such microorganisms to one or more antibiotics or other types of anti-infectives are disclosed herein. More specifically, methods for quantifying microorganisms based on redox reactions are disclosed along with systems and devices for quantifying such microorganisms using certain oxidation reduction potential (ORP) sensors. Moreover, methods for determining the susceptibility and the degree of susceptibility of microorganisms to one or more anti-infectives are disclosed along with multiplex systems for such assays.

Apparatus, systems, and methods for determining the concentration of microorganisms and the susceptibility of microorganisms to anti-infectives based on redox reactions

Various devices, systems and methods for detecting infectious agents or determining a susceptibility of an infectious agent to an anti-infective are described herein. One example method comprises introducing a fluid sample to a surface; exposing the surface to a solution; sampling the solution after exposing the solution to the surface; and detecting a change in an electrical characteristic of a sensing device exposed to the solution sampled corresponding to a presence of the infectious agent in the fluid sample.

Devices, systems and methods to detect viable infectious agents in a fluid sample and susceptibility of infectious agents to anti-infectives

The devices and method described herein allow for therapeutic damage to increase volume in these hyperdynamic hearts to allow improved physiology and ventricular filling and to reduce diastolic filling pressure by making the ventricle less stiff.

Methods and devices for diastolic assist

Various apparatus, systems, and methods for measuring a solution characteristic of a sample comprising microorganisms are disclosed. The measured solution characteristic can be used to generate a standardized inoculum. In one embodiment, a sensor apparatus is disclosed comprising a sample container having a chamber lateral wall surrounding a chamber cavity configured receive the sample, a reference sensor fabricated as a container cap and comprising a reference electrode material and, and an active sensor made of a substrate covered in part by an active electrode layer. The active sensor can be coupled to at least part of the chamber lateral wall at a window opening defined along the chamber lateral wall. The solution characteristic can be measured using a reader configured to electrically couple to the sensor apparatus and measure the solution characteristic based on a potential difference between the active sensor and the active sensor.

Devices, systems, and methods for preparing a standardized inoculum for antimicrobial susceptibility testing

Methods and devices for diagnosing, monitoring, and/or treating tissue through an opening or port through an airway wall are provided herein.

Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall

Fluid flow control devices for medical use are disclosed. On one end, a fluid flow control device is configured to be attached to a manifold that is in-line with an infusion setup and the other end of the fluid flow control device is configured to be attached to a sampling or infusion device, such as a syringe. In one aspect, a fluid flow control device has an external casing and an internal casing which is configured to be movably housed within the external casing. The internal casing mates with a fluid outlet on the external casing and upon separating the internal and external casings a fluid flow path is established.

Medical devices and methods for fluid transfer

Described herein are syringe devices, systems and methods. In general, the syringe may include a first chamber and a cartridge movable within the first chamber. The cartridge may include a cartridge chamber and a valve in fluid communication with the cartridge chamber and the first chamber and having an open configuration and a closed configuration. The valve may allow movement of a liquid out of the cartridge chamber while in a open configuration. The cartridge may also include a second end, movable within the cartridge chamber, and a locking mechanism having a locked configuration and an unlocked configuration, the locking mechanism preventing movement of the second end within the cartridge chamber while in the locked configuration.

Methods and devices for autoflush syringes

Growing community of inventors

Menlo Park, CA, United States of America

Michael D Laufer