Omeros Corporation

Plexera, LLC

Michael Cicirelli

Jennifer Lynn Gage

Thomas L Little, Jr

Neil S Cutshall

Peter Kurt Nollert Von Specht

Markus Metz

Sara Rebecca Goldstein

Jennifer Tsoung

Do Yeon Kwon

Santosh Kumar Keshipeddy

Robert Huerta Lemus

Jeremiah H Nguyen

Sudheer Babu Vaddela

Juhienah Khalaf

Timothy C Parker

Ronald P Dudek

Franz A Gruswitz

Loren Michael Price

The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds.

MASP-2 inhibitors and methods of use

The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds, and methods of making and using such compounds.

This disclosure describes methods and compositions for measuring the binding specificity, kinetics and affinity of kinase inhibitors indirectly using mass sensing analytical techniques, such as SPR, through the competitive displacement of detectable signal-inducing kinase binding molecule. Further provided are methods for preparing such molecules.

Label free kinase assays and reagents

Growing community of inventors

Kirkland, WA, United States of America

Michael Cicirelli