Affymetrix, Inc.

Perlegen Sciences, Inc.

Michael C Norris

Peter E Lobban

Donald M Besemer

Andrew B Carlson

Steven V Muller

Mark O Trulson

Methods and devices are provided for using high-density arrays of diverse chemical entities. In preferred embodiments, small volumes of multiple liquids are delivered to multiple reaction sites on a single substrate where the liquids are constrained to localized reaction sites. The substrate need not be cut apart prior to being used for analysis. Accordingly, the area of the substrate on which analysis may be performed is maximized. In many embodiments of the present invention, constraining regions hinder the transport of liquids between adjacent reaction sites.

Liquid delivery devices and methods

A device for transporting cartridges comprises a housing for holding a plurality of cartridges in a temperature controlled environment. A transport system is also provided and has a grasping mechanism for grasping one of the cartridges. The transport system is further used to remove the cartridge from the housing and to place the cartridge into a scanner.

Cartridge loader and methods

The present invention generally provides novel apparatuses for rapidly and efficiently carrying out repeated hybridizations of a target nucleic acid to an array of nucleic acid probes. The apparatus generally includes a fluid delivery system, a fluid mixing system, a temperature control system and a process control system integrated into a single device.

Fluidics station injection needles with distal end and side ports and method of using

Fluidics station with a mounting system and method of using

Growing community of inventors

Santa Clara, CA, United States of America

Michael C Norris