Iowa State University Research Foundation, Inc.

University of Utah Research Foundation

Michael C Granger

Marc D Porter

Mark Christopher Tondra

Ruth Shinar

Robert J Lipert

Jing Ni

G Brent Dawson

Jooneon Park

Discrete magnetic nanoparticles synthesized using a layer-by-layer technique are disclosed. The nanoparticles contain a magnetic core having a large magnetic moment, a plurality of layers and an exterior coating. The nanoparticles have utility in a wide range of biological and bioanalytical applications.

Discrete magnetic nanoparticles

Method and apparatus for manipulating and monitoring analyte flowing in fluid streams. A giant magnetoresistive sensor has an array of sensing elements that produce electrical output signals which vary in dependence on changes in the magnetic field proximate the sensing elements. The analyte is included in a stream, such that the stream has a magnetic property which is dependent on the concentration and distribution on the analyte therein. The stream is flowed past the giant magnetoresistive sensor and in sufficiently close proximity to cause the magnetic properties of the stream to produce electrical output signals. The electrical output signals are monitored as an indicator of analyte concentration or distribution in the stream flowing past the GMR sensor. Changes in the magnetic field produced by the background stream are introduced by analyte molecules, whose presence in the flow past the GMR will effect the output reading.

Method and apparatus for magnetoresistive monitoring of analytes in flow streams

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Salt Lake City, UT, United States of America

Michael C Granger