Block Drug Company, Inc.

Michael C Alfano

Tiang-shing Chang

Kuo-Chen Yeh

Joseph D Synodis

Alfred J Smetana

Frank J Sena

John M Gardella

Emanual S Troullos

Casimir Ciepierski

Joseph Kanapka

Ronald S Leight

Tiang-Shing Chang

An oral composition for treatment of hypersensitive teeth in which the salty taste of the desensitizing salt, such as a potassium or strontium salt, is masked by baking soda, sodium bicarbonate.

Taste masked desensitizing compositions

A method for reducing bone resorption at tooth extraction sites by topically applying a prostaglandin inhibitor, such as a non-steroidal anti-inflammatory drug (NSAID) to the affected area. The preferred NSAID is ketoprofen. The composition may also include a penetration enhancer such as vitamin E.

Bone regeneration

This invention relates to a mild oral hygiene composition such as a toothpaste, dental gel, mouthrinse or tooth powder containing a mild surfactant, protein fatty acid condensate or acid hydrolyzed, hydrolyzed animal protein or the mixtures thereof, and in combination therewith, mild high foaming surfactant, e.g., disodium cocoamido MIPA sulfosuccinate or disodium oleamido PEG-2 sulfosuccinate or disodium lauryl sulfosuccinate or the mixtures thereof; or a natural emulsifier, e.g., lecithin, or both a mild surfactant and a nautral emulsifier.

Taste preserving, mild oral hygiene compositions

Synergistic compositions comprising an antioxidant and an arylpropionic, non-steroidal anti-imflammatory drug used to treat certain diseases are disclosed. The compositions inhibit production of arachidonic acid cascade end-products which have been implicated as causes of tissue-destruction in periodontal disease. The compositions are administered in combination with a carrier, which may be a mucosal-tenacious polymer selected from the groups of semi-solid pastes, gels, ointments, liquids or films.

Compositions and method for the treatment of disease

Dental tool handle

A dental prophylactic device has a handle section containing a drive member and a driven section at a substantial angle to the handle section containing a driven member also at an angle to the driving member. The handle section includes a longitudinally oscillatable cam follower supported parallel to the handle axis. When the cam follower is translated around the axis by the rotation of the drive shaft, it is caused to oscillate by one end contacting the stationary cam follower track. The other end engages a slot parallel to the axis of a cam at an angle to the cam follower thereby causing the cam to oscillate back and forth over an arc of at least 50.degree. to approximately 150.degree., maintaining the connection between the cam follower and the cam by the use of the slot which permits the cam follower, in effect, to move up and down with respect to the cam as it oscillates. The cam oscillates a cup which may contain prophylactic material and the reversing action limits the ability of the material to be thrown out of the cup and obviates unintended movement of the cup over the surface of a tooth which occurs in the case of rotation in a single direction. A special sealing ring and its compartment, remotely located from the head of the spindle, provides an excellent seal.

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Franklin Lakes, NJ, United States of America

Michael C Alfano