Duke University

Michael Brown

Darell D Bigner

Matthias Gromeier

Smita K Nair

Smita Nair

Mathias Gromeier

Chimeric poliovirus is capable of activating antigen presenting cells. The activation of the antigen presenting cells may be in vitro, ex vivo, or in vivo. The activated antigen presenting cells may be administered alone or with an antigen or vaccine. The activated antigen may be loaded in vitro or ex vivo with antigen to form antigen-loaded, activated, antigen presenting cells. These may be administered therapeutically. Therapeutic administration of antigen presenting cells may be used as an adjuvant to other therapies.

Growing community of inventors

Durham, NC, United States of America

Michael Brown