Behringwerke Aktiengesellschaft

Other

Behring Diagnostics Gmbh

Chiron Behring Gmbh & Co.

Behring Diagnositcs Gmbh

Movartis Ag

Novartis Vaccines & Diagnostics, Gmbh

Michael Broker

Bernhard W Fleckenstein

Gerhard Jahn

Michael Mach

Bernd Traupe

Birgit-Christine Scholl

Bernd Meyhack

Mathias Fibi

Horst Domdey

Klaus-Dieter Hungerer

Bernhard Knapp

Bernd-Ulrich Von Specht

Torsten Lowin

Susanne Modrow

Markus Mobs

Johann Hock

The invention relates to a modified VP1-capsid protein of parvovirus B19 having a reduced phospholipase A2-like enzyme activity as compared to the wild type VP1-capsid protein of parvovirus B19 having the amino acid sequence of SeqID 1.

Modified VP1-capsid protein of parvovirus B19

Process for the production of proteins

The invention relates to novel Schizosaccharomyces-specific proteins and their antibodies. These proteins and antibodies can be used for identifying the yeast genus Schizosaccharomyces.

Schizosaccharomyces-specific polypeptides

The present invention relates to a hybrid protein comprising the Pseudomonas aeruginosa outer membrane protein I (OprI) which is fused with its amino terminal end to the carboxy-terminal end of a carboxy-terminal portion of the Pseudomonas aeruginosa outer membrane protein F (OprF), as well as to monoclonal or polyclonal antibodies against this hybrid protein. Both, the hybrid protein and the antibodies directed to the hybrid protein confer protection against an infection by Pseudomonas aeruginosa to laboratory animals or man.

Immunogenic hybrid protein OprF-OprI derived from Pseudomonas aeruginosa

The phosphorylated structural protein of molecular weight about 150 kd (pp 150) of human cytomegalovirus (HCMV) is highly immunogenic and is reliably recognised by human antisera. This protein can, after assignment and sequencing of the gene, be prepared, in whole or in immunogenic sections, by gene manipulation. Proteins of this type are suitable as reagents, for example in an ELISA, and as constituents of vaccines.

Structural phosphoprotein (PP150) of human cytomegalovirus, and the

Peptide of the structural phosphoprotein (pp 150) of human

Particularly suitable expression vectors for the synthesis of proteins in the fission yeast Schizosaccharomyces pombe (S. pombe) are described. These expression vectors are (in addition to other advantageous elements, equipped with a strong homologous promoter and terminator).

Expression vectors for the synthesis of proteins in the fission yeast

A method for degrading nucleic acids in a waste fermentation solution is disclosed. The method comprises exposing the waste solution to RNases and/or DNases released by autolysis of and/or secreted from Paecilomyces lilaninus which are present in or added to the waste solution. The fermentation of the microorganism occurs under sterile conditions. The microorganism can be transformed with nuclease-encoding genes and added to the waste solution before fermentation. The preferred strain of Paecilomyces lilacinus is DSM 5650.

Method for degrading nucleic acids in waste fermentation solutions with

Growing community of inventors

Marburg, Germany

Michael Broker