Bayer Healthcare LLC

Bayer Pharmaceuticals Corporation

Bayer Healthcare Aktiengesellschaft

Michael Brands

Julie A Dixon

Donald Bierer

Wenlang Fu

Brian Richard Bear

Dhanapalan Nagarathnam

Barton W Phillips

Steven R Magnuson

Alexander Hillisch

Benjamin Jones

Martin F Hentemann

Yuanwei Chen

Jianmei Fan

Ming Wang

Harold C E Kluender

Brent Chandler

Jianqing Chen

Ann-Marie Bullion

Catherine R Brennan

Lin Yi

Karl Miranda

Chunguang Wang

Andrea McClure

Lei Zhang

Johannes-Peter Stasch

Manoj Patel

Hanno Wild

Thomas Krahn

Stefan Weigand

Jens-Kerim Ergüden

Christian Schröder

Harold C Kluender

Andrea Mcclure

This invention relates to pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.

Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis

Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R, G, G', and G&#x2033; represent substituent groups and Rrepresents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.

Pyrimidine derivatives for treatment of hyperproliferative disorders

Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R, G, G', and G&#x2033; represent substituent groups and Rrepresents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed. 

This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.

The invention relates to compounds of formula (I), to a method for the production thereof, and to the use of the same as pharmaceuticals for the treatment of diseases in humans and/or animals 

Substituted 2,5-diamidoindoles as ECE inhibitors for the treatment of cardiovascular diseases

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Hamden, CT, United States of America

Michael Brands