Elwha LLC

Other

Tokitae LLC

The Invention Science Fund I LLC

Michael Baym

Lowell L Wood, Jr

Roderick A Hyde

Jordin T Kare

Elizabeth A Sweeney

Nathan P Myhrvold

Clarence T Tegreene

Eric Leuthardt

Tony S Pan

Muriel Y Ishikawa

Gary L McKnight

Mahalaxmi Gita Bangera

Edward K Y Jung

Victoria Y H Wood

Charles Whitmer

Philip Andrew Eckhoff

William David Duncan

W Daniel Hillis

Dennis James Rivet, Ii

Michael A Smith

Conor L Myhrvold

Roy P Diaz

Robert W Lord

Richard T Lord

Katherine E Sharadin

Ralph G Dacey, Jr

Erez Lieberman

Terry Briggs

Clark J Gilbert

Daniel Jay MacDonald

Karima R Nigmatulina

Edward Stuart Boyden

Jesse R Cheatham, Iii

Hon Wah Chin

Paul D Holman

Bonnie Berger Leighton

Po-Ru Loh

Pablos Holman

Erez Lieberman Aiden

Philip A Welkhoff

Lev Shaket

Oluwakemi Adesina

Robert Dunne

Buz Barstow

Isao Anzai

Systems and methods for isolating DNA molecules that can include the steps of: providing a transposon mutant collection, the transposon mutant collection being stored in a plurality of wells; dispatching aliquots from each well in the transposon mutant collection to a set of pools in a combinatorial pooling array that uses pool address coordinates, the aliquots being dispatched to the set of pools based on a location of the aliquots within the transposon mutant collection; constructing an amplicon library, the amplicon library including a sequencing dataset; parsing the sequencing dataset to a set of putative transposon insertion locations and pool address coordinates; calculating a likelihood for each location and pool address coordinates within the set of putative transposon insertion locations and pool address coordinates using a Bayesian inference algorithm informed by internal self-consistency; and generating a progenitor collection catalog based on location and pool address coordinates verified in the calculating step.

Method for isolating DNA molecules by generating a progenitor collection catalog

Embodiments disclosed herein relate to methods, devices, and computer systems thereof for automated data collection from a subject. In certain embodiments, one or more characteristics of a subject are sensed, and the subject is given a queue status indicator based on a comparison of the subject's one or more sensed characteristics with corresponding sensed characteristics from other subjects. In one embodiment, the subject is a healthcare worker and the system, methods, and devices are utilized to evaluate the overall health of the worker as part of the check-in process for work.

Devices, systems, and methods for automated data collection

The redundancy in genomic sequence data is exploited by compressing sequence data in such a way as to allow direct computation on the compressed data using methods that are referred to herein as 'compressive' algorithms. This approach reduces the task of computing on many similar genomes to only slightly more than that of operating on just one. In this approach, the redundancy among genomes is translated into computational acceleration by storing genomes in a compressed format that respects the structure of similarities and differences important to analysis. Specifically, these differences are the nucleotide substitutions, insertions, deletions, and rearrangements introduced by evolution. Once such a compressed library has been created, analysis is performed on it in time proportional to its compressed size, rather than having to reconstruct the full data set every time one wishes to query it.

Compressing, storing and searching sequence data

Devices and methods for profiling microbiota of skin are described which include a microbe profiling device including a device head and a hand-held housing, the device head including an epidermis-engaging component and an access window and configured to dislodge microbes from a skin surface, and the hand-held housing defining an opening aligned with the access window, the hand-held housing including a motor operably coupled to a motivatable component, a substrate disposed in relation to the motivatable component and including a microbe-capture region, a location-capture component to detect a location of one or more regions of the skin surface as the epidermis-engaging component contacts said one or more regions, at least one sensor component to detect one or more signals emitted or reflected from the microbe-capture region, and a computing component including circuitry to associate the location of said one or more regions of the skin surface and the detected one or more signals.

Devices and methods for profiling microbiota of skin

A computationally implemented system and method that is designed to, but is not limited to: electronically determining positioning status of one or more portions of one or more humans relative to one or more locations of demodulation of one or more acoustic ultrasonic signals into one or more acoustic audio signals said one or more acoustic ultrasonic signals originating from a portable electronic device; and electronically alerting said one or more humans from said portable electronic device regarding said positioning status of one or more portions of one or more humans relative to one or more locations of demodulation of one or more acoustic ultrasonic signals into one or more acoustic audio signals when said positioning status includes a first characterization. In addition to the foregoing, other method aspects are described in the claims, drawings, and text forming a part of the present disclosure.

Portable electronic device directed audio emitter arrangement system and method

Systems and methods are described for modifying a cosmetic product based on a microbe profile including an ingredient-microbe interaction dataset including information associated with interactions between reference cosmetic ingredients and types of reference microbes; and a computing device including circuitry configured to receive information associated with the microbe profile of an individual, receive information associated with an ingredient list of the cosmetic product, compare the microbe profile of the individual and the ingredient list of the cosmetic product to the ingredient-microbe interaction dataset, identify an interaction between at least one cosmetic ingredient in the ingredient list of the cosmetic product and at least one of the one or more types of microbes in the microbe profile of the individual, recommend a modification to the ingredient list in response to an identified interaction, and report to a user the recommended modification.

Modifying a cosmetic product based on a microbe profile

A computationally implemented system and method that is designed to, but is not limited to: electronically providing audio output information to one or more portions of a portable electronic device to be outputted from said portable electronic device via one or more acoustic ultrasonic signals; and electronically outputting, said one or more acoustic ultrasonic signals to be demodulated into one or more acoustic audio signals containing one or more portions of said audio output information at one or more locations spaced from said portable electronic device based at least in part according to said one or more acoustic ultrasonic signals and based at least in part according to one or more portable electronic device ultrasonic emitter arrangements. In addition to the foregoing, other method aspects are described in the claims, drawings, and text forming a part of the present disclosure.

Portable electronic device directed audio system and method

Devices, systems, and methods for assessing microbiota of skin are described, including: a skin-covering material including an inner surface and an outer surface, the inner surface substantially conforming to a topography of a skin surface of an individual and including a plurality of signal-generating complexes, one or more of the plurality of signal-generating complexes configured to emit one or more signals in response to at least one type of microbe; an image capture device to capture an image of the inner surface of the skin-covering material, the image including one or more signals emitted from the plurality of signal-generating complexes, and to transform the image into a digital output; and a computing device including circuitry configured to receive the digital output, compare the properties of the imaged one or more signals with a database of reference signal-generating complexes, and generate a digital spatial profile of microbes on the skin-covering material.

Systems, methods, and devices for assessing microbiota of skin

Apparatus, system, and method are disclosed herein for controlling movement of an artificial orthopedic joint prosthesis in a mammalian subject. The apparatus, system, or method includes an orthopedic brace configured to control movement of an orthopedic joint prosthesis. The apparatus, system, or method includes one or more sensors and one or more controllers in communication with the one or more sensors. The one or more sensors are configured to detect a change in an orientation of a subject's position in an environment and configured to detect one or more alignment orientations of the orthopedic joint prosthesis.

Apparatus, system, and method for controlling movement of an orthopedic joint prosthesis in a mammalian subject

A system for capturing an image of a user includes a mobile device for requesting capture of the image of the user and a camera. The mobile device further includes a communications device configured to broadcast a request, a user input device, and a processing circuit structured to instruct the communications device to broadcast the request in response to an input received via the user input device. The camera is configured to receive the broadcasted request, determine the location of the user, and capture an image of the user.

Mobile device for requesting the capture of an image

Robotic debridement apparatuses, related systems, and methods of using the same are disclosed herein. The robotic debridement apparatuses are configured to facilitate debridement of tissue from a wound region. For example, the robotic debridement apparatuses can include one or more of at least one debriding tool configured to debride tissue, at least one tissue disposal tool configured to dispose of substances in the wound region, to the wound region. The systems disclosed herein can include a plurality of robotic debridement apparatuses. The systems disclosed herein can include a dressing associated with the plurality of robotic debridement apparatuses. The dressing can be associated with the robotic debridement apparatuses in a manner that facilitates operations of the robotic debridement apparatuses.

Robotic debridement apparatuses, and related systems and methods

Systems and methods for competency training and use authorization for dispensing an agent are described, which include: an agent-dispensing device configured to dispense one or more agents to a user, and including a controllable agent-dispensing mechanism and a receiver configured to receive a signal and to activate or deactivate a locking mechanism coupled to the controllable agent-dispensing mechanism; a computing device having a display and a user interface; and a web-based interactive tool accessible on the computing device, the web-based interactive tool including a training module to provide training to the user in proper use of the agent-dispensing device, a verification module to verify a competency of the user in the proper use of the agent-dispensing device, and an activation module responsive to the verification module and operable to provide an activation signal to deactivate the locking mechanism to allow dispensing of the one or more agents after verifying the competency of the user.

Systems and methods for competency training and use authorization for dispensing an agent

Systems, devices, and methods are described for tracking, registering, etc. of medical staff, patients, instrumentation, events, or the like according to a treatment staging plan. For example a medical apparatus includes a right-patient verification device having an interrogation interface device that elicits at least one of identification data, authorization data, or treatment plan data from a medical procedure authorization device associated with a patient; and a right-site verification device that generates patient-specific treatment staging data consistent with the at least one of the identification data, the authorization data, or the treatment plan data.

Electronically determining compliance of a medical treatment of a subject with a medical treatment plan for the subject

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Cambridge, MA, United States of America

Michael Baym