Research Institute at Nationwide Children's Hospital

The Ohio State University

Michael Bailey

Steven David Goodman

Gail E Besner

Lauren Opremcak Bakaletz

Provided herein are methods and probiotic compositions for treating or preventing a disease or neurodevelopmental deficiency in a subject in need thereof using the compositions. Aspects and embodiments of this technology combine the health benefits of probiotic bacteria with prebiotic substances to help stimulate the exclusive growth of the probiotic species and, in one aspect, provide the bacteria in the form of a biofilm on a biocompatible microsphere.

Prebiotic formulations for prevention of sepsis and necroenterocolitis induced neurodevelopmental deficiencies

Provided herein are compositions comprising a biocompatible microsphere, a biofilm-generating probiotic bacterium, a prebiotic, and/or a prebiofilmic. Methods for preparing and formulating the compositions and methods for treating or preventing a disease using the compositions are also provided.

Growing community of inventors

Columbus, OH, United States of America

Michael Bailey