Quest Diagnostics Investments, Inc.

Michael Aye

Michelle M Tabb

Maurice Exner

Jules Chen

Huong Mai

Lilly I Kong

Fan Chen

Ming-Chou Lee

Luca Jacky

Yin-Peng Chen

Ning Lu

Lakshmi Nair

Heather Vincent

Emberlee Eleazar

Provided herein are methods for identifying the presence or absence of a target nucleic acid from a microorganism using direct amplification without a step of extraction of the nucleic acids, but retaining substantially the same specificity and sensitivity of methods assaying extracted nucleic acids.

Direct amplification and detection of viral and bacterial pathogens

Disclosed herein are methods and compositions for detectingandby detecting the presence of the IS481 and IS1001 genomic insertion sequences, respectively.

Bordetella detection assay

detection assay

Disclosed are methods of identifying a methicillin-resistant(MRSA) in a sample wherein the methods involve detecting a-specific nucleic acid sequence, mecA and mecC, in the sample. Kits for determining the presence of MRSA in a sample are also provided.

Detection of methicillin-resistantin biological samples

The present invention generally relates to a molecular test of Influenza A, Influenza B, Respiratory Syncytial Virus A, and Respiratory Syncytial Virus B in order to identify patients with a viral infection. Accordingly methods and compositions are disclosed to determine the presence or absence of a viral pathogen in a sample containing one or more target nucleic acids from the M gene of Influenza A, Influenza B, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B.

Multiplex detection assay for influenza and RSV viruses

Provided are methods for identifying the presence or absence of a target nucleic acid from a microorganism using direct amplification without a step of extraction of the nucleic acids, but retaining substantially the same specificity and sensitivity of methods assaying extracted nucleic acids. Further provided are reagent mixtures that allow for direct amplification of a sample, without the step of nucleic acid extraction.

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Huntington Beach, CA, United States of America

Michael Aye