Human Genome Sciences, Inc.

Michael Antonaccio

Craig A Rosen

Steven M Ruben

Mark D Adams

Haodong Li

Brent L Kreider

Donna Mendrick

Pablo Jimenez

Vikram P Patel

Reiner L Gentz

There are disclosed therapeutic compositions and methods using isolated nucleic acid molecules encoding a human myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptide (previously termed MIP-3 and chemokine &#x3b2;8 (CK&#x3b2;8 or ckb-8)); a human monocyte-colony inhibitory factor (M-CIF) polypeptide (previously termed MIP1-&#x3b3; and chemokine &#x3b2;1 (CK&#x3b2;1 or ckb-1)), and a macrophage inhibitory protein-4 (MIP-4), as well as MPIF-1, M-CIF and/or MIP-4 polypeptides themselves, as are vectors, host cells and recombinant methods for producing the same.

Myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptides

There are disclosed therapeutic compositions and methods using isolated nucleic acid molecules encoding a human myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptide (previously termed MIP-3 and chemokine &#x3b2;8 (CK&#x3b2;8 or ckb-8)); a human monocyte-colony inhibitory factor (M-CIF) polypeptide (previously termed MIP1-&#x3b3; and chemokine &#x3b2;1(CK&#x3b2;1 or ckb-1)), and a macrophage inhibitory protein-4 (MIP-4), as well as MPIF-1, M-CIF and/or MIP-4 polypeptides themselves, as are vectors, host cells and recombinant methods for producing the same.

Antibodies to myeloid progenitor inhibitory factor-1 (MPIF-1)

Antibodies to monocyte-colony inhibitory factor (M-CIF)

There are disclosed therapeutic compositions and methods using a human monocyte-colony inhibitory factor (M-CIF) polypeptide (previously termed MIP1-&ggr; chemokine &bgr;1(CK&bgr;1 or ckb-1)), as well as ioslated nucleic acid molecules encoding M-CIF, and vectors, host cells and recombinant methods for producing the same.

Human monocyte colony inhibitory factor (M-CIF) polypeptides

Growing community of inventors

New Hope, PA, United States of America

Michael Antonaccio