Quantum Applied Science & Research, Inc.

Electronic Biosciences, Inc.

Michael Andrew Krupka

Andrew Dennis Hibbs

Eric N Ervin

Robert Matthews

Vanja Panic

Eric Mayo Peterson

John Andrew Wisniewski

Devices and methods are provided that utilize two adjacent nanopore readers for sequencing of a polymer or a portion thereof.

Adjacent dual biological nanopore readers

A system for measuring a free space electric field includes an ultrahigh impedance antenna positioned in the electric field to generate a signal from the electric field. An amplifier having an input port is provided to amplify the signal. The amplifier generates an input bias current which combines with the signal to create an input potential at the input port. An electrical circuit connects the input port to a ground connection and includes at least one circuit element for controlling the input potential to stabilize the signal at the input port.

Low noise, electric field sensor

A system for measuring a biopotential signal produced by a body in free space at a location adjacent to the body, and if desired, through clothing, includes a probe that can be positioned adjacent to the body. The probe includes a conductive electrode to receive the biopotential signal and a conductor that is maintained at a fixed distance from the electrode. The potential of the conductor can be maintained substantially equal to the potential of the electrode to shield the electrode from stray electrical noise. The system further includes a high impedance first stage amplifier that is incorporated into the probe and electrically connected to the electrode using a relatively short connector to minimize connector noise. Functionally, the first stage amplifier compares the electrical potential of the electrode to a second potential (e.g. a local ground) and generates a signal that is indicative of the biopotential.

Sensor system for measuring biopotentials

An electronic circuit stabilizes an ultrahigh input impedance amplifier by altering the amplifier's input potential. This input potential includes both the desired input signal and the amplifier's input bias current. With an amplifier having an input port and a guard, both the input port and the guard will have the same input potential. Accordingly, the stabilizing circuit of the present invention provides the input potential at the guard to an electronic device which separates the input signal from the input bias current. This creates a corrective signal. The corrective signal is then used through a feedback path to alter the input potential so that the desired input signal can be fed into the amplifier without adverse consequences from the input bias current.

Growing community of inventors

San Diego, CA, United States of America

Michael Andrew Krupka