Dow Agrosciences LLC

Dow Global Technolgoies LLC

Dowelanco

Michael Allen Gonzalez

Gary A Roth

Michael Rack

Joachim Gebhardt

Guido Mayer

Weishi W Wu

David Craig Molzahn

Hagen Jaedicke

Norbert Götz

Jon A Orvik

Mark Andrew Pobanz

Daniel Randolph Henton

Christopher Thomas Hamilton

Timothy J Adaway

James William Ringer

Eric W Otterbacher

Jimmy J Tai

David Bruce Gorman

Douglas L Pearson

Michael Gullo

Dawn L Shiang

Anne P Wallin

Thomas A Olmstead

Michael Glenn Smith

The present invention relates to selective partial oxidation of methane in the absence of a solvent such as sulfuric acid or oleum.

Process for selective, partial, substantially solvent-free, oxidation of methane to methanol and/or a methanol derivative with a heterogeneous catalyst and sulfur trioxide

4-Trifluoromethyl-2(1H)-pyridinone is prepared by reaction of 4-alkoxy-1,1,1-trifluorobut-3-en-2-one or 4,4-dialkoxy-1,1,1-trifluorobutan-2-one with a trialkyl phosphonoacetate followed by cyclization.

Process for the preparation of 4-trifluoromethyl-2(1H)-pyridinone

A method for preparing a composition of the formulain a yield greater than 50% where Ris C 1-20 comprising the steps of combining fluorene or dibromo flourene, an excess of alkali metal hydroxide and a halogenated alkyl in the presence of a phase transfer catalyst but in the absence of a polar aprotic solvent; heating the combination; and separating the dialkylated fluorene or dialylated dibromo fluorene. If the flourene is not brominated prior to alkylation, the dialkylated fluorene is then brominated.

Method for producing substituted fluorene monomers

3-Substituted benzotrifluorides are selectively deprotonated and functionalized in the 2-position. The selectivity is achieved by equilibrating the mixture of lithiobenzotrifluorides initially formed in the presence of a primary or secondary amine catalyst.

Process for the selective deprotonation and functionalization of 3-substituted benzotrifluorides

2-Alkoxy-6-trifluoromethyl-N-(&lsqb;1,2,4&rsqb;triazolo&lsqb;1,5-c&rsqb;pyrimidin-2-yl)benzenesulfonamides are prepared by introducing the 2-alkoxy substituent of the benzenesulfonamide ring in the last step by contacting the corresponding 2-fluoro substituted material with the appropriate alkoxide.

Process for the preparation of 2-alkoxy-6-trifluoromethyl-N-(&lsqb;1,2,4&rsqb;triazolo&lsqb;1,5-c&rsqb;pyrimidin-2-yl) benzenesulfonamides

2-Chlorosulfonyl-5-alkoxy[1,2,4]triazolo-[1,5-c]pyrimidine compounds, such as 2-chlorosulfonyl-5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidine, that are useful for the preparation of 5-alkoxy[1,2,4]triazolo [1,5-c]pyrimidine-2-sulfonamide herbicides, were prepared in an improved manner from 5-alkoxy[1,2,4]triazolo [1,5-c]pyrimidine-2(3H)-thione compounds, such as 5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thione, by oxidation with hydrogen peroxide to obtain novel 2,2'-dithiobis(5-alkoxy[1,2,4]triazolo[1,5-c]pyrimidine) compounds, such as 2,2'-dithiobis (5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidine), and subsequent chloroxidation of these intermediate compounds.

5-alkoxy[1,2,4]triazolo[1,5-c]pyrimidine-2(3H)--thione compounds and

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Sanford, MI, United States of America

Michael Allen Gonzalez