Bar-ilan University

Biomas Inc.

Other

Tellus Biotech Ltd.

Cassiopea S.p.a.

Feramda Ltd.

Michael Albeck

Benjamin Sredni

Shlomo Grossman

Leo Pavliv

Doron Friedman

Ascher Shmulewitz

Gideon Strassmann

Doron Firedman

Novel formulations of tellurium-containing compounds, which are suitable for topical application, are disclosed. The formulations are characterized by high chemical and physical stability and are easy to handle and use.

Topical formulations of tellurium-containing compounds

A novel method for treating skin and mucosal membrane ailments caused by human papilloma viruses, which utilizes tellurium-containing compounds, is disclosed. Also disclosed are pharmaceutical compositions containing tellurium-containing compounds for treating such ailments.

Therapeutic methods and pharmaceutical compositions for treating warts with tellurium compounds

Methods for treating skin conditions such as basal cell carcinoma and/or actinic keratosis are provided, which are effected by administering a pharmaceutically effective amount of a tellurium-containing compound. A pharmaceutical composition for treatment of skin conditions such as basal cell carcinoma an/or actinic keratosis is also provided.

Use of tellurium compounds for the treatment of actinic keratosis

Use of tellurium-containing compounds for treating conditions in which inhibition of caspase-1/interleuFkin-1&#x3b2; enzyme (ICE) is beneficial is disclosed.

Use of tellurium compounds for inhibition of interleukin-converting enzyme

Use of tellurium compounds for protection from ultra-violet radiation

The invention relates to an aqueous solution containing at least one species selected from the group consisting of a 1:1 molar complex of TeOwith a moiety of formula (A) and ammonium salts thereof:HO&#x2014;X&#x2014;OH &#x2003;&#x2003;(A)where X is an optionally substituted divalent saturated hydrocarbon group containing 2-8 carbon atoms in the chain connecting the two OH groups; and its use for stimulating cells to produce cytokines and for treating mammalian diseases and conditions responsive to increased production of cytokines. The complex may be used also for treating mammalian cancer which is not responsive to increased production of cytokines.

Biologically active complex

The invention relates to an aqueous solution containing at least one species selected from the group consisting of a 1:1 molar complex of TeOwith a moiety of formula (A) and ammonium salts thereof: HO&#x2014;X&#x2014;OH (A); where X is an optionally substituted divalent saturated hydrocarbon group containing 2-8 carbon atoms in the chain connecting the two OH groups; and its use for stimulating cells to produce cytokines and for treating mammalian diseases and conditions responsive to increased production of cytokines. The complex may be used also for treating mammalian cancer which is not responsive to increased production of cytokines.

Use of tellurium-containing compounds for treating conditions in which inhibition of caspase-1/interleukin-1&#x3b2; enzyme (ICE) is beneficial is disclosed.

Novel tellurium-containing compounds and uses thereof as immunomodulators are disclosed.

Tellurium compounds and their use as immunomodulators

A novel neuroprotective agent is disclosed for the treatment and prevention of neurodegenerative disorders which is based on the administration of an effective amount of a tellurium compound which has a specific ability to induce the differentiation and interfere with apoptotic cell death pathways of neuronal PC-12 cells.

Use of tellurium containing compounds as nerve protecting agents

A novel nutrient formulation containing tellurium for use in poultry, and a method of feeding it which improves subsequent livability, cumulative feed efficacy or weight gain is disclosed.

Tellurium containing nutrient formulation and process for enhancing the cumulative weight gain or feed efficacy in poultry

The present application discloses a method of treating alopecia which is based on the use of a tellurium compound such as ammonium trichloro(dioxoethylene-O,O-tellurate).

Method of treating or preventing alopecia

The invention comprises the administration of an effective amount of a tellurium compound to a patients who is afflicted with psoriasis. The tellurium compound is administered either systemically or topically to one who is afflicted with psoriasis in an amount which is effective to alleviate the symptoms of psoriasis.

Growing community of inventors

Ramat Gan, Israel

Michael Albeck