Schering Corporation

Michael A Zupon

Joel A Sequeira

Imtiaz A Chaudry

Zachary Yim

Pui-Ho C Yuen

Alan S Kirschner

An insoluble zinc-protamine alpha interferon complex useful as an injectable sustained release dosage form for administering alpha interferon is disclosed.

Zinc-protamine-alpha interferon complex

Stable oleaginous gels comprising water-in-oil emulsions in gels are disclosed. Sustained release injectable pharmaceutical formulations comprising such oleaginous gels are also disclosed, in particular such formulations comprising interferon.

Stable oleaginous gel

A topical albuterol composition having superior transdermal flux containing various amounts of albuterol, 1-dodecyl-azacycloheptan-2-one and urea in a non-aqueous environment. The enhancement observed in albuterol skin penetration indicates that a therapeutically effective amount of albuterol can be delivered through skin using these formulations. The compositions can be administered topically as a cream, lotion or via a transdermal device.

Compositions and method for enhancement of the transdermal flux of

Albuterol sulfate syrups that are pleasant-tasting and stable upon prolonged storage.

Stable pleasant-tasting albuterol sulfate pharmaceutical formulations

Disclosed is a kit for preparing a lyophilized alpha interferon gel formulation suitable for topical administration.

Growing community of inventors

Madison, NJ, United States of America

Michael A Zupon