The Invention Science Fund I LLC

Elwha LLC

Searete LLC

Gearbox LLC

Deep Science, LLC

Somne LLC

Battelle Energy Alliance, LLC

Strategic Analytics, Inc.

Seavete LLC

Hyde, Roderick, A.

Caldeira, Kenneth G.

Wood, Lowell, L., Jr.

Smith, Michael A.

Rivet, Dennis J.

Michael A Smith

Roderick A Hyde

Eric Leuthardt

Lowell L Wood, Jr

Muriel Y Ishikawa

Dennis James Rivet, Ii

Victoria Y H Wood

Clarence T Tegreene

Nathan P Myhrvold

Edward Stuart Boyden

Jordin T Kare

Elizabeth A Sweeney

Gregory J Della Rocca

Charles Whitmer

Edward K Y Jung

Thomas A Weaver

Ralph G Dacey, Jr

Robert Samuel Langer

Daniel Hawkins

Parag Jitendra Parikh

Terence Myckatyn

Joshua S Shimony

Robert W Lord

Joshua L Dowling

Eleanor V Goodall

Gregory Zipfel

Colin Derdeyn

Mahalaxmi Gita Bangera

Hon Wah Chin

Jeffrey A Bowers

Michael Baym

Paul Duesterhoft

Roy P Diaz

Stephen L Malaska

Kenneth G Caldeira

Glenn B Foster

Sharon L Wolda

Mark A Malamud

Royce A Levien

John D Rinaldo, Jr

W Daniel Hillis

Paul G Allen

Richard Neil Zare

Gary L McKnight

Erez Lieberman

Paul Santiago

Todd J Stewart

Katherine A Sharadin

Leif T Stordal

Erez Lieberman Aiden

James L Jones

Joseph L Breeden

Alan W Hunt

J Frank Harmon

R David Franklin

Robert Langer

Randy J Spaulding

Dennis J Rivet

Eric C Leuthardt

Dennis J Ii Rivet

An embodiment of a system for treating sleep apnea includes a collar, pump, motor, sensor, memory, and controller, which is configured to store, in the memory, information related to sleep-apnea events or sleep-apnea treatment, experienced by the subject. For example, the controller can obtain, and store in the memory, information related to sleep-apnea events, and the controller, or another computing system, can correlate this information with the subject's lifestyle choices, and can recommend lifestyle changes to improve the subject's sleep apnea. Furthermore, the controller can obtain and store, in the memory, information related to usage and settings of the sleep-apnea system, and the controller, or another computing system, can correlate this information with the subject's wellbeing, and can recommend changes in the usage or the settings of the sleep-apnea system that can improve the subject's wellbeing.

Obtaining, with a sleep-apnea device, information related to sleep-apnea events and sleep-apnea treatment, and correlating sleep apnea events and sleep-apnea treatment with subject lifestyle and wellbeing

The present disclosure provides systems and methods associated with acoustic transmitters, receivers, and antennas. Specifically, the present disclosure provides a transducer system for transmitting and receiving acoustic energy according to a determined acoustic emission/reception pattern. In various embodiments, an acoustic transducer system may include an array of sub-wavelength transducer elements each configured with an electromagnetic resonance at one of a plurality of electromagnetic frequencies. Each sub-wavelength transducer element may generate an acoustic emission in response to the electromagnetic resonance. A beam-forming controller may cause electromagnetic energy to be transmitted at select electromagnetic frequencies to cause a select subset of the sub-wavelength transducer elements to generate acoustic emissions according to a selectable acoustic transmission pattern. A common port may facilitate electromagnetic communication with each of the sub-wavelength transducer elements.

Steerable acoustic resonating transducer systems and methods

An embodiment of a system for treating sleep apnea includes a collar, a pump, a motor, a sensor, and a controller. The collar is configured to maintain an airway of a subject open while the subject is sleeping by applying, to a throat of the subject, a negative pressure having a magnitude, and the pump is configured to generate the negative pressure. The motor is configured to drive the pump, and the sensor is configured to generate a sense signal that is related to a degree to which the airway is open. And the controller is configured to vary the magnitude of the negative pressure in response to the sense signal. For example, one or more of the pump, motor, sensor, and controller can be secured to the collar such that the system is self-contained, i.e., the entire sleep-apnea system can be worn by the subject.

Treating sleep apnea with negative pressure

A system can perform the following procedure as part of a plan to treat sleep apnea, according to an embodiment. The system monitors a degree to which an airway of a subject is open, and monitors a condition that is related to the degree to which the airway is open. The system also correlates the condition to the degree to which the airway is open, and generates a data structure that represents the correlation between the condition and the degree to which the airway is open. This system can allow a sleep-apnea-treatment system to operate in a closed-loop mode, i.e., to monitor a level of sleep apnea in a subject by monitoring the correlated condition, and to treat the subject in a manner that the treatment system deems appropriate for the level of sleep apnea that the treatment system determines that the subject is experiencing.

Correlating a condition of a subject with a degree of sleep apnea being experienced by the subject

Methods and systems for monitoring compliance of a patient with a prescribed treatment regimen are described. Patient activity is detected unobtrusively with an activity sensor at the patient location, and activity data is transmitted to a monitoring location. Patient speech detected during use of a communication system such as a mobile telephone by the patient may also be used as an activity signal. Patient activity and/or speech is processed at the patient location or monitoring location to identify activity parameters or patterns that indicate whether the patient has complied with the prescribed treatment regimen. The activity sensor and other components at the patient location may be incorporated into, or associated with, a cell phone, computing system, game system, or vehicle system, for example. The system may provide a report to an interested party, for example a medical care provider or insurance company, regarding patient compliance with the prescribed treatment regimen.

Monitoring treatment compliance using patient activity patterns

Systems, devices, and methods are described for tracking, registering, etc. of medical staff, patients, instrumentation, events, or the like according to a treatment staging plan. For example a medical apparatus includes a right-patient verification device having an interrogation interface device that elicits at least one of identification data, authorization data, or treatment plan data from a medical procedure authorization device associated with a patient; and a right-site verification device that generates patient-specific treatment staging data consistent with the at least one of the identification data, the authorization data, or the treatment plan data.

Electronically determining compliance of a medical treatment of a subject with a medical treatment plan for the subject

Systems and methods for wearable injection guides are described, which include: acquiring one or more digital images of a body region of an individual with at least one image capture device; creating a digitally rendered model of a wearable injection guide from the one or more digital images of the body region of the individual; adding one or more digitally rendered fiducials indicative of at least one treatment parameter to the digitally rendered model of the wearable injection guide; and forming the wearable injection guide from the digitally rendered model of the wearable injection guide, the formed wearable injection guide including one or more fiducials corresponding to the one or more digitally rendered fiducials on the digitally rendered model of the wearable injection guide.

Systems and methods for wearable injection guides

Systems and methods are described herein for guided injection, which include: one or more controllable light-emitting elements configured to emit non-destructive light and a computing device operably connected to the one or more controllable light-emitting elements configured to emit non-destructive light, the computing device including a processor operable to receive at least one digital representation of a body region of an individual, the body region of the individual including one or more physical registration landmarks, the at least one digital representation including one or more digitally registered injection sites and one or more digital registration landmarks corresponding to the one or more physical registration landmarks on the body region; and control the one or more controllable light-emitting elements to illuminate a location of a surface of the body region of the individual corresponding in location to at least one of the one or more digitally registered injection sites.

Systems and methods for guiding injections

Methods and related systems for modulating neural activity by repetitively blocking conduction in peripheral neural structures with chemical blocking agents are disclosed. Methods and systems for reversing effects of chemical blocking agents and/or for producing substantially permanent conduction block are also disclosed.

Method and system for modulating neural activity

System and methods are described herein for generating an injection guide, which include receiving one or more digital images of a body region of an individual, the body region including one or more physical registration landmarks, generating at least one digital representation of the body region using the one or more digital images, the at least one digital representation including one or more digital registration landmarks corresponding to the one or more physical registration landmarks on the body region, adding one or more digitally registered injection sites to the at least one digital representation of the body region in an injection-treatment pattern, the one or more digitally registered injection sites registered relative to the one or more digital registration landmarks, and generating one or more output signals having information for controlling one or more controllable light-emitting elements to illuminate a location on a surface of the body region of the individual corresponding in location to at least one of the one or more digitally registered injection sites.

Systems and methods for generating an injection guide

Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the plurality of sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.

Breast implant with analyte sensors responsive to external power source

A method includes a method implemented in a medical apparatus implanted in an animal and configured to at least one of transmit or receive a communication externally of the animal. The method includes receiving a communication. The method also includes detecting an indication of a malware in the received communication. The method further includes implementing in the implanted medical device a countermeasure responsive to the detected indication of malware in the received communication.

Secure operation of implanted device

A device and methods are disclosed herein for fluid removal during wound treatment or for removal or dialysis of components from blood or tissue. A device is disclosed that includes a multilayer membrane including a plurality of layers; an electroactive polymer within each layer; and a controller operably connected to sequentially activate the electroactive polymer to alter one or more sizes of the plurality of the variably-sized pores within one or more layers of the multilayer membrane. A device is disclosed that includes a multilayer membrane including a plurality of layers; an actuator operably attached to the plurality of layers of the multilayer membrane; and a controller operably activating the actuator to alter a relative lateral position of the two or more layers of the multilayer membrane to align two or more of the plurality of pores within the plurality of layers of the multilayer membrane.

Device including multilayer membrane to control fluid drainage and methods of use thereof

Systems, devices, and method for determining treatment compliance including tracking, registering, etc. of medical staff, patients, instrumentation, events, etc. according to a treatment staging plan

Growing community of inventors

Phoenix, AZ, United States of America

Michael A Smith