Other

Zenith Epigenetics Corp.

Microsoft Technology Licensing, LLC

Hewlett-packard Company

Merck Sharp + Dohme Corp.

University of Virginia

Sequoia Sciences, Inc.

Mercator Genetics, Inc.

Ispeedbuy, LLC

Michael A Ellis

Shuang Liu

He Zhao

John Frederick Quinn

May Xiaowu Jiang

Peter Ronald Young

Bryan Cordell Duffy

Gregory Scott Martin

Gregory Steven Wagner

Ruifang Wang

Jared N Cumming

William F Walker

Jack D Scott

Timothy A Blizzard

Gary R Eldridge

David Andrew Ruddy

Timothy Allen Blizzard

Ronald Buckle

Bruce E Kimmel

Bryan O Washington

Zhongping Huang

Greg Hermann

Benjamin Cammarano

John Edward Reilly

Dan Ayoub

Ronald Neil Buckle

A nozzle system for a carpet drying machine includes two or more planar diffusion plates each having a manifold side and a carpet side. The diffusion plates each include a plurality of apertures traversing from the manifold side to the carpet side. Each aperture is wider at the manifold side than at the carpet side so as to define a concentrating nozzle through the diffusion plate. Preferably the concentrating nozzles of each diffusion plate flare outwardly progressively increasingly from the carpet side of the diffusion plate to the manifold side of the diffusion plate. As such, with the two or more diffusion plates mounted in two or more manifolds of the carpet drying machine, with the manifold side of the diffusion plate facing away from the carpet web, hot air blown into the manifolds is concentrated into a laminar flow towards the carpet web to dry the carpet web.

Nozzle plates for a carpet dryer

An apparatus for coating carpet webs in a coating apparatus with varying adhesives includes a controller, one or more sensors for detecting a volume of a puddle of the adhesive pooled in front of an application roller, and an electronic valve in fluid communication with each of a plurality of mixers. The electronic valve directs flow of the adhesive from any of the mixers to the coating apparatus. To switch from one of the adhesives to new adhesive as a next carpet web passes through the coating apparatus, the controller calculates a remaining length of the carpet web that can be coated with the adhesive in the puddle of adhesive based on the volume of the puddle, so that the puddle of the adhesive coats the carpet web, and then proximate a seam to the next carpet web, the new adhesive begins to coat the next carpet web.

Adhesive applicator control system

The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

Substituted bicyclic compounds as bromodomain inhibitors

A modular continuous mixer includes a rigid casing having an inlet adjacent to an annular inlet end thereof and an outlet adjacent an opposing annular outlet end thereof. The casing further includes a cylindrical exterior casing wall that, together with the ends, define a volume therein. The ends each include a plurality of concentric rings of mixing pins projecting into the volume. One or more rotor disks are rotationally fixed within the casing between distal ends of the opposing pins. Each rotor disk includes a plurality of the concentric rings of mixing pins projecting from both sides thereof toward the inlet and outlet ends. A drive shaft is rotatably mounted in the casing and fixed through the center of each rotor disk. Additional casing extensions can be mounted between the inlet and outlet ends of the casing to facilitate further mixing.

Modular continuous adhesive foam mixer

The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy. 

Various embodiments relating to providing touch input control of a computing device are disclosed. In one example, responsive to detecting a touch input on a display, a zero point of an adaptive virtual control may be established at a display location of the touch input. Responsive to a translation of the touch input on the display away from the zero point being greater than a radius of the adaptive virtual control, the zero point may be translated.

Adaptive touch input controls

An approach for creation of an electrical vault cover that is able to generate power that is stored in a battery for use by a heater to maintain the temperature above a minimum in a utility vault.

Electric vault cover

In its many embodiments, the present invention provides certain C-6 spirocarbocyclic iminothiadiazine compounds, including compounds Formula (I): or a tautomers thereof, and pharmaceutically acceptable salts of said compounds and said tautomers, wherein R, R, ring A, R, m, L, and RL are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimer's disease, are also disclosed. 

C-6 spirocarbocyclic iminothiadiazine dioxides as BACE inhibitors, compositions, and their use

A carpet backing system for applying a coating to a roll of carpet includes elongated upper deck having a first end and a second end. An elongated lower deck is situated below and aligned with the upper deck. The upper deck includes a staging and unrolling station at a first end thereof, a pre-coat applicator for applying a pre-coat to the carpet, and an oven station to cure the pre-coat and allow the carpet to exit a second end of the upper deck. The lower deck includes a polymer applicator at a first end thereof for receiving the carpet and the pre-coat from the second end of the upper deck. The polymer applicator is adapted to apply the coating to the carpet. The lower deck further includes a heating platen conveyor, a plurality of cooling rolls, and optionally a carpet rolling station at a second end of the lower deck.

Carpet tile coating system and method

An applicator device applies at least one liquid to a first side of a flexible web, such as a web of carpet material. A pair of application stations each comprises at least a pair of parallel rollers each driven by a roller motor arrangement. A platen directs the web between the rollers. Two dams are each laterally adjustable with respect to a top roller and conform to the shape of the top roller at a forward end thereof. Each of the dams, the top roller, and the web define a puddle area to which one of the at least one liquid is applied for application to the web as the web moves between the pair of rollers. A rigid frame fixes a first application station in a substantially horizontal orientation, and a second of the application stations in a substantially vertical orientation, with a turning roller situated therebetween.

Liquid application system for a flexible web

One or more systems, methods, or computer program products can include receiving an echo data set including information representative of an echo sensed by a transducer, provided at least in part by one or more actual targets included in a region of interest. The region of interest can be modeled, including selecting or generating an array manifold matrix including information corresponding to any one or more candidate targets. The weights of the candidate targets can be determined using the array manifold matrix and the echo data set, including minimizing an argument of a function modeling the weights of the candidate targets. In an example, the echo data set can be dithered, such as by adding a specified dithering signal.

Time-domain estimator for image reconstruction

A text message paging and ordering system utilizes a dedicated or shared short code to enable an establishment, such as a restaurant, to send pages to mobile communication devices, such as a mobile phone. Transmitted text messages sent from the establishment are associated with a short code, which allows the mobile communication device in receipt of the text message to send reply messages back to the establishment associated with the short code. As such, this provides a wireless carrier approved medium that reliably and readily enables an establishment to have two-way text communication with a customer or client to facilitate paging functions as well as ordering functions.

Growing community of inventors

Chickamauga, GA, United States of America

Michael A Ellis