Cartiva, Inc.

Carticept Medical, Inc.

Arris International, Inc.

Michael A Axelrod

Timothy J Patrick

Carribeth B Ramey

Letitia Tudor

Richard Knostman

Craig B Berky

Jonathan P Bauer

Ernest N Corrao, Jr

Jeremy Hemingway

Steven P Walsh

Ernest N Corrao

A tool configured to deliver a radially compressible hydrogel implant at a surgical site includes an introducer tube, a plunger provided inside the introducer tube and configured to travel from the proximal end of the introducer tube toward the distal end of the introducer tube urging the hydrogel implant through a sloped portion of the introducer tube radially compressing the implant before exiting through the distal end of the introducer tube, a handle connected to the introducer tube, and a clamp hingeably connected to the handle.

Implant introducer

An implant system includes a first portion, a second portion, and a third portion. The first portion includes a hydrogel; the second portion includes a porous material and the hydrogel in pores of the porous material; and the third portion includes the porous material. The first portion is free of the porous material and the third portion is free of the hydrogel. The third portion has non-uniform lateral cross-section.

Hydrogel implants with porous materials and methods

Provided is a kit for treating tissue of a subject. The kit includes a tool for creating a wedge opening within a bone tissue, and an implant. In some examples, the kit also includes an introducer configured to deliver the implant into the wedge opening.

Tooling for creating tapered opening in tissue and related methods

A method of creating a wedge-shaped recess in a bone is disclosed. The method includes creating a cylindrical recess within a bone, positioning a tool within the cylindrical recess, radially expanding an articulating cutter of the tool and rotating the tool to remove additional bone along the cylindrical recess' side walls and create a wedge-shaped recess; wherein, a diameter of the bottom surface of the wedge-shaped recess is larger than a diameter of a surface opening of the wedge-shaped recess.

Devices and methods for creating wedge-shaped recesses

According to some embodiments, a method of creating for creating a reverse tapered opening within tissue comprises creating a cylindrical opening within a targeted anatomical site of a subject using a first device and removing additional tissue from the sidewalls of the cylindrical opening using a cutting member to create a reverse tapered opening within the targeted anatomical site using a second device, wherein, once the reverse tapered opening is created, a diameter or other cross-sectional dimension of a bottom surface of the opening is larger than a diameter or other cross-sectional dimension of a top surface of the opening.

An implant system includes a first portion, a second portion, and a third portion. The first portion includes a hydrogel. The second portion includes a porous material and the hydrogel in pores of the porous material. The third portion includes the porous material. The first portion is free of the porous material. The third portion is free of the hydrogel. Methods of making and using the implant system.

According to some embodiments, a method of treating a joint of a patient comprises creating a recess in a bone located at or near a targeted joint, wherein the recess includes a generally wedge or truncated cone shape. In one embodiment, the recess in a bone comprises a surface opening along an outer surface of the bone and a bottom opening along the distal end of the recess, such that a diameter of the surface opening is generally smaller than a diameter of the bottom opening. The method additionally comprises providing a joint implant having a wedge or truncated cone shape, wherein a diameter of a top end of the joint implant is generally smaller than a diameter of a bottom end of the joint implant, inserting the joint implant within the recess.

Methods of repairing a joint using a wedge-shaped implant

Systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, an intra-articular space, include a handpiece assembly having a proximal end and a distal end, a needle extending from the distal end of the handpiece assembly, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medications, formulations and/or other fluids or materials contained within vials that are secured to the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.

Removable cassette for articular injection system

Devices and systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, a joint or intra-articular space, include a handpiece assembly having a needle extending from its distal end, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medicaments, formulations and/or other fluids or materials contained within vials that are secured to a cassette or other portion of the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.

System for injecting fluids in a subject

Devices and systems for injecting fluids, such as anesthetics, to or near nerve tissue or other targeted anatomical location are disclosed herein. A conduit is generally configured to place the fluid delivery module in fluid communication with a needle that is configured to be inserted into the patient's anatomy. One or more medicaments (e.g., anesthetics) and/or other materials contained within containers (e.g., vials) that are secured to the injection system can be selectively delivered into an anatomy through the needle. Nerve stimulation and/or imaging technologies (e.g., ultrasound) can be used to locate a targeted anatomical location. Aspiration can be used to confirm needle location. An overlay on the imaging display can include, in addition to real-time imaging data, data and other information relating to back pressure at or near the needle tip, volumes or other amounts of fluids delivered by and remaining within the system, stimulation level and/or the like.

Growing community of inventors

Roswell, GA, United States of America

Michael A Axelrod