Bioalpha Corporation

Mi Young Ryu

Jun Hyuk Seo

Hyun Seung Ryu

Sung Nam Park

Gyu Dong Jang

So Myoung Lee

Nam Yul Cho

Baek Il Kim

The present invention relates to a method for preparing a medical material for replacing a hard tissue defect and a medical material produced therefrom. More specifically, in the present invention, powders of bioactive glass are press-molded, and are then subjected to a first heat treatment at a relatively low temperature below the glass transition temperature of bioactive glass. Then, the resultant is processed into a desired shape and then subjected to a second heat treatment at a temperature higher than the glass transition temperature of bioactive glass. Accordingly, the present invention provides a medical material which can be customized to a desired shape of a hard tissue defect in a living body and minimize thermal shock, and which is capable of exhibiting a bone fusion property, while overcoming the low compressive strength drawback of hydroxyapatite, which is an existing hard tissue replacement material currently in use.

Method for preparing a medical material for replacing a hard tissue defect and a medical material prepared therefrom

The present invention relates to a crystallized glass ceramic comprising 30 wt % to 40 wt % of each of CaSiO, Ca(PO)(OH), and CaMg(SiO); a crystallized glass ceramic composition comprising CaSiO, Ca(PO)(OH), and CaMg(SiO) in a predetermined weight ratio; a bone graft material comprising the glass ceramic; and an intervertebral spacer or medical device for replacement of bone tissue, which is manufactured using the bone graft material.

High-strength crystallized glass ceramic comprising wollastonite, hydroxyapatite and akermanite

The present invention relates to a bone graft composition and a preparation method thereof, and more particularly to a bone graft composition having excellent physical properties, which comprises a hydrogel comprising a combination of specific amounts of poloxamer and HPMC, and calcium phosphate compound particles, and a preparation method thereof.

Bone graft composition and preparation method thereof

Disclosed herein is a method for preparing an aqueous solution of high-concentration calcium phosphate, the method comprising the steps of: preparing an acidic aqueous solution using an acidic chelating agent; and dissolving a calcium phosphate-based compound in the acidic aqueous solution, and then adding a pH-adjusting agent to the acidic aqueous solution to adjust the pH of the acidic aqueous solution. The disclosed aqueous solution does not form a precipitate after neutralization so that it can be used in various calcium-containing products, including foods, drugs, or quasi-drugs.

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Gyeonggi-do, South Korea

Mi Young Ryu